Q2KNL6 · GEDH1_OCIBA

Function

function

Involved in the production of citral, a mixture of geranial and neral with a strong lemony scent. Reversibly oxidizes geraniol and nerol in equal efficiency. Also active, although at a lower efficiency, with cinnamyl alcohol.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Activity regulation

66% inhibition by 5 mM Zn2+.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
655 μMcinnamyl alcohol
30 μMgeraniol
37 μMnerol
Vmax pH TEMPERATURE[C] NOTES EVIDENCE
23 pmol/sec/ugtoward cinnamyl alcohol
13 pmol/sec/ugtoward geraniol
19 pmol/sec/ugtoward nerol

pH Dependence

Optimum pH is 9.5. Active from pH 8.5 to 10.0.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site50Zn2+ 1 (UniProtKB | ChEBI); catalytic
Binding site72Zn2+ 1 (UniProtKB | ChEBI); catalytic
Binding site103Zn2+ 2 (UniProtKB | ChEBI)
Binding site106Zn2+ 2 (UniProtKB | ChEBI)
Binding site109Zn2+ 2 (UniProtKB | ChEBI)
Binding site117Zn2+ 2 (UniProtKB | ChEBI)
Binding site166Zn2+ 1 (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Molecular Functiongeraniol dehydrogenase activity
Molecular Functionzinc ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Geraniol dehydrogenase 1
  • EC number
  • Short names
    ObaGEDH1

Gene names

    • Name
      GEDH1

Organism names

  • Taxonomic identifier
  • Strain
    • cv. SD
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Lamiales > Lamiaceae > Nepetoideae > Ocimeae > Ociminae > Ocimum

Accessions

  • Primary accession
    Q2KNL6

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003670521-360Geraniol dehydrogenase 1

Expression

Tissue specificity

Expressed in leaves, with a very low expression in peltate glands.

Structure

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    360
  • Mass (Da)
    39,044
  • Last updated
    2006-03-07 v1
  • Checksum
    0D53B63806C33253
MAKSPETEHPVKALGWAATDNSGTFSPFNFSRRATGERDVQFRVLYCGVCHSDLHMVKNEWGVTHYPIVPGHEIVGIVTEVGSKVEKVKIGDKVGVGVLVGSCRQCDQCSNDLENYCYKQILTYGAPYLDGTIARGGYSDIMVADEHFIIRWPENFPLDAGAPLLCAGITTYSPLKYFGLDKPGLRVGVNGLGGLGHVAVKFAKAFGTKVTVISTSLSKKEEAMQHLGVDEFVVSTDPQQMQAAVGTLDGIIDTVSAPHPIVPLLSLLKPHGKLIVVGLPDKPLQLPVFPLIQGRRTIAGSGIGGLKETQEMIDFAAKNNIVADVEVIPIDYINTAMDRLLKSDVKYRFVIDVEKSLKPQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY879284
EMBL· GenBank· DDBJ
AAX83107.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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