Q2KN97 · CYTSA_CHICK

Function

function

Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentfilamentous actin
Cellular Componentgap junction
Cellular Componentmicrotubule organizing center
Cellular Componentspindle
Biological Processactin cytoskeleton organization
Biological Processcell division

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytospin-A
  • Alternative names
    • SPECC1-like protein
    • Sperm antigen with calponin homology and coiled-coil domains 1-like

Gene names

    • Name
      SPECC1L
    • Synonyms
      CYTSA

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus

Accessions

  • Primary accession
    Q2KN97

Proteomes

Organism-specific databases

Subcellular Location

Note: Colocalizes with beta-tubulin, acetylated alpha-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center (By similarity).

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002310221-1118Cytospin-A

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

May interact with both microtubules and actin cytoskeleton.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, coiled coil, domain.

TypeIDPosition(s)Description
Region1-176Disordered
Compositional bias14-53Polar residues
Compositional bias73-119Polar residues
Compositional bias120-134Basic and acidic residues
Compositional bias136-153Polar residues
Compositional bias154-176Basic and acidic residues
Coiled coil193-281
Compositional bias299-319Polar residues
Region299-324Disordered
Region359-391Disordered
Coiled coil396-450
Coiled coil488-808
Region856-879Disordered
Compositional bias863-877Pro residues
Region921-1002Disordered
Compositional bias967-991Polar residues
Domain1012-1117Calponin-homology (CH)

Sequence similarities

Belongs to the cytospin-A family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,118
  • Mass (Da)
    124,909
  • Last updated
    2006-04-04 v2
  • Checksum
    8BADEFEFCCF8096A
MKKASRSVGSVPKVPGVNKTQTTEKTKPESGSSLSAVTKLSKPGTSASLLKTKSNDDLLAGMASGGGVTMTNGVKAKKSTCASTVSSTTGTTMSTLENKPRTVAGSTARRSTSSGTKESSSSRERIRDRSRLSQSKKLPLAGQGSNDTVLAKRSRSRTNPESDIRMSKSKSDNQISDKAALEAKVNDLLTLAKTKDVEILHLRNELRDMRAQLGLNEDQVEGDEKSEEKEAIVVHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITAGNHSDGGGTLTSSVEGSAPGSMEDLLSQDEHTLMDNQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGVPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTAEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDMKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERNHHMERIIESEQKSKTAIASTLEEYKATVASDQIEMNRLKAQLEHEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEELAHTRNDANRLQDAIAKVEDEYRVFQEEAKKQIEDLNVTLEKLRAELDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKNLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPSPAAATIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISASKPLATLTDKRPSYAEIPVQEHLLRTSSTSRPASLPRVPAMESAKSISVSRRSSEEIKRDISAPDGASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCAVLHTYLPAHIPYQELNSQDKRRNFTLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET

Sequence caution

The sequence AAX84189.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias14-53Polar residues
Compositional bias73-119Polar residues
Compositional bias120-134Basic and acidic residues
Compositional bias136-153Polar residues
Compositional bias154-176Basic and acidic residues
Compositional bias299-319Polar residues
Compositional bias863-877Pro residues
Compositional bias967-991Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY884298
EMBL· GenBank· DDBJ
AAX84189.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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