Q2J542 · ISPD_FRACC

Function

function

Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.

Features

Showing features for site.

TypeIDPosition(s)Description
Site26Transition state stabilizer
Site33Transition state stabilizer
Site161Positions MEP for the nucleophilic attack
Site214Positions MEP for the nucleophilic attack

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
  • EC number
  • Alternative names
    • 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
    • MEP cytidylyltransferase
      (MCT
      )

Gene names

    • Name
      ispD
    • Ordered locus names
      Francci3_4254

Organism names

Accessions

  • Primary accession
    Q2J542

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002377901-2662-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias234-248Basic and acidic residues
Region234-266Disordered

Sequence similarities

Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    266
  • Mass (Da)
    27,498
  • Last updated
    2006-03-07 v1
  • Checksum
    7BB80635E9F23974
MGEGHRLPVASPRVAAIVPAAGRGERLGGGTPKALRALGGRPMLVRTVESLRRSRLVTQIVVAAPPTLVDAVAQLLGGDVYVIAGGAERVDSVRRALRAVDDDVSVVLVHDAARPLTPPELVDAVAAAVLDGHPAVIPVVPLADTVKEVDADGRVVRTPPRDGLRAVQTPQGFRRDVLSAAYALEDIAVTDDAGLVEALGVPVTTIPGAQEAFKVTRPADLVLAEALLARCDPADDARSAEARSAEARSEEPQFAGARSTDARSGG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias234-248Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000249
EMBL· GenBank· DDBJ
ABD13600.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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