Q2FIF3 · NMO_STAA3

Function

function

Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), the presumed physiological substrate. Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.

Miscellaneous

P3N is a potent irreversible inhibitor of the key enzyme succinate dehydrogenase in the Krebs cycle and electron transport chain. P3N has been shown to be a toxic metabolite to bacteria, plants, fungi, mammals or any organism that uses succinate dehydrogenase.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Note: Binds 1 FMN per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site71FMN (UniProtKB | ChEBI)
Binding site175FMN (UniProtKB | ChEBI)
Binding site180FMN (UniProtKB | ChEBI)
Binding site218FMN (UniProtKB | ChEBI)
Binding site237-240FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionnitronate monooxygenase activity
Molecular Functionnucleotide binding
Biological Processresponse to toxic substance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable nitronate monooxygenase
  • EC number
  • Short names
    NMO
  • Alternative names
    • Propionate 3-nitronate monooxygenase (P3N monooxygenase)

Gene names

    • Ordered locus names
      SAUSA300_0825

Organism names

Accessions

  • Primary accession
    Q2FIF3

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003609011-355Probable nitronate monooxygenase

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    355
  • Mass (Da)
    38,548
  • Last updated
    2006-03-21 v1
  • Checksum
    2ABD713D5FDA7DB6
MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIGAGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLEEPVVKITEEQQFKCHIDTIIKKQVPVCCFTFGIPSEQIISRLKAANVKLIGTATSVDEAIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGGIMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVITKAFSGKLARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELIHMWSGQSPRLATTHPANTIMSNIINQINQIMQYK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000255
EMBL· GenBank· DDBJ
ABD22280.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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