Q29428 · TKDP1_SHEEP

  • Protein
    Trophoblast Kunitz domain protein 1
  • Gene
    TKDP1
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

May play a role in mediating maternal-conceptus interactions in the immediate preimplantation period. Does not seem to have proteinase inhibitory activity.

Features

Showing features for site.

126520406080100120140160180200220240260
TypeIDPosition(s)Description
Site218-219Reactive bond homolog

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Molecular Functionserine-type endopeptidase inhibitor activity

Names & Taxonomy

Protein names

  • Recommended name
    Trophoblast Kunitz domain protein 1
  • Short names
    TKDP-1

Gene names

    • Name
      TKDP1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Caprinae > Ovis

Accessions

  • Primary accession
    Q29428

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation, disulfide bond.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_000001688021-265Trophoblast Kunitz domain protein 1
Glycosylation95N-linked (GlcNAc...) asparagine
Glycosylation180N-linked (GlcNAc...) asparagine
Disulfide bond208↔258
Disulfide bond217↔241
Glycosylation218N-linked (GlcNAc...) asparagine
Disulfide bond233↔254

Keywords

PTM databases

Expression

Tissue specificity

Expressed only in the trophectoderm, which forms the outer epithelial layer of the trophoblast.

Developmental stage

Maximal expression at days 14 and 16 of pregnancy.

Structure

Family & Domains

Features

Showing features for repeat, region, domain.

TypeIDPosition(s)Description
Repeat32-1151
Region32-2002 X 84 AA approximate repeats
Repeat117-2002
Domain208-258BPTI/Kunitz inhibitor

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    265
  • Mass (Da)
    28,964
  • Last updated
    1996-11-01 v1
  • Checksum
    D700805DF03E3132
MRQLCLSTALLFLLVILVDSTPLNIYHIQDEGLETSHRRGPEKRSVIDVVSGIINGVATGTKIIEKGAGILTGLAEIITKAIKGQVMISRIQFDNHTLEELPTLQLEYSTLSEENNGLKTSHRRGLEKRSVTDVVTSIINGVATGTKIIEKGAGILTGLAEIITKAIKGQVMISGIQFDNHTLEEYQTLKIEYSTLSEENKASKPALCLEPKVTGDCNATMTRYFYNTQTGLCEQFVYTGCEGNGNNFENLEDCMKTCSQEAGSL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U00165
EMBL· GenBank· DDBJ
AAA19108.1
EMBL· GenBank· DDBJ
Unassigned DNA
L11343
EMBL· GenBank· DDBJ
AAB46361.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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