Q280D5 · Q280D5_9CYAN
- ProteinGlutamate--tRNA ligase
- GenegltX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids480 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Catalytic activity
- tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | glutamate-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Molecular Function | zinc ion binding | |
Biological Process | glutamyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamate--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Nostocales > Tolypothrichaceae > Tolypothrix
Accessions
- Primary accessionQ280D5
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-317 | Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic | ||||
Sequence: VRVRIAPSPTGNLHIGTARTAVFNWLFARHHGGKFILRIEDTDLERSRPEYTENILEGLRWLGLNWDEGPFFQSQRLDLYKQAVEKLLAQGLAYRCYTTSEELEALREAQKAKGEAPRYDNRHRNLTPEQEAAFKAEGRSFVIRFKIEDDREIVWDDLVRGKMSWRGSDLGGDMVIARASEDGVGQPLYNFVVVVDDIDMQITHVIRGEDHIANTAKQILLYEAMGAKIPQFAHSPLILNMEGRKLSKRDGVTSISDFQQLGFTSEGLVNYMTLLGWSPPDSTQEIFTLEAAAKEFSFERVNKAGAKFDWAKLDW | ||||||
Motif | 9-19 | 'HIGH' region | ||||
Sequence: PSPTGNLHIGT | ||||||
Motif | 247-251 | 'KMSKS' region | ||||
Sequence: KLSKR | ||||||
Domain | 330-464 | Aminoacyl-tRNA synthetase class I anticodon-binding | ||||
Sequence: QLTDLLIPYWEAAGFNFDGGRDRAWLEQLVALLGPSLTRLKDAVAQSQLFFTETVEFSEEASKQLQQEGSAAVLQGILAALETQELQEATAQEIIKQVVKAQNVKKGLVMRSLRAALTGDVHGPDLIQSWLLLHK |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length480
- Mass (Da)54,004
- Last updated2006-04-04 v1
- ChecksumBFED771AADE29444
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DQ257628 EMBL· GenBank· DDBJ | ABC94738.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AGCR01000068 EMBL· GenBank· DDBJ | EKE99655.1 EMBL· GenBank· DDBJ | Genomic DNA |