Q27JK7 · Q27JK7_XENTR

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site, active site.

1925100200300400500600700800900
Type
IDPosition(s)Description
Binding site363Zn2+ (UniProtKB | ChEBI); catalytic
Active site364
Binding site367Zn2+ (UniProtKB | ChEBI); catalytic
Binding site373Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processproteolysis

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Submitted names
    • ADAM12
    • Disintegrin and metalloproteinase domain-containing protein 12 precursor

Gene names

    • Name
      adam12
    • Synonyms
      mcmp
      , MCMPMltna
      , mltn
      , mltna

Organism names

Accessions

  • Primary accession
    Q27JK7

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane722-742Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-33
ChainPRO_503320626534-925
Disulfide bond495↔515
Disulfide bond673↔683
Disulfide bond691↔700

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain227-429Peptidase M12B
Domain437-523Disintegrin
Domain669-701EGF-like
Region893-925Disordered
Compositional bias905-925Pro residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    925
  • Mass (Da)
    101,827
  • Last updated
    2006-04-04 v1
  • Checksum
    168C01AE808F919C
MSESLRAEQRGFLPLHLLILLLCLSWGVIPSQAQGENVEGKLESSRQQTEKEKHEHYEIIVPYLLRGEEWEAIGSVSTKSHPPAMKVLLKAKDIRLLISLERNKGLFAGNFSTTHYTEDGVFVSTALNYTDHCYYHGKVEGYSESSVSVSSCSGLRGLITLENRAYVLEPQANSTTSHLFYQAEHLKLISGSCSQHFNLSGVSLSDNFQHSQDTFKRHKRDTVKTTKYVELVIVADNREYQRQGKDVDKVKHRLIGMANYVDKFFRPLNIRVALVGVEIWSDSDKCSITQDPFTTLQEFLDWRKLKLLPQKPHDNAQLVSGVYFQGTTIGMAPIMSMCTADKSGGIVMDHSGNPLGAAVTLAHELGHNFGMNHDTLERGCNCRGSADNGGCIMTPSTAYPFPTVFSSCGKKDLDSSLEKGVGMCLYNMPEVTESFGEQKCGNGYVEEGEQCDCGEPDECTNPCCNASLCMLKPGAVCAHGLCCEDCKLKPAGTPCRDANNFCDLPEFCSGTSAHCPANVYLHDGHPCFKIEGYCYNGVCQTHEQQCITLWGQGAKPAPGICFERVNSAGDPYGNCGKDSTGSFTKCENRDAKCGKIQCQGGANRPVIGTNAVSIETNIPLQEGRRILCRGTHVYLGDDLPDPGLVLAGTKCEEGKICLNRKCQNISIFGVHDCALKCHGHGVCNNKKNCHCEAEWAPPFCDKHGFGGSVDSGPVRLHDNRSLITGMIVTIGCIFLAAFIVYLKRKTLFQWLFSNKKTTIEKLRSVRPSRGGCSNEPNQEYRTALSKHVLSKPACPPKEESSIQYNTRLPRCHPIDISHPIRILELPQHSLPRKVQAPLHSLPFQQTVPARPLPAKPSVRCLQGSCIPSPPQKPLPAVPLNKTSQSDSALGTMFEHREHVPRITPVRPAPKCPPQQPGPTKPPQRK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias905-925Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ393787
EMBL· GenBank· DDBJ
ABD52382.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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