Q27393 · Q27393_DROME

Function

Catalytic activity

Features

Showing features for binding site, active site.

142150100150200250300350400
TypeIDPosition(s)Description
Binding site174ATP (UniProtKB | ChEBI)
Binding site193ATP (UniProtKB | ChEBI)
Binding site242-244ATP (UniProtKB | ChEBI)
Active site289Proton acceptor
Binding site293-294ATP (UniProtKB | ChEBI)
Binding site307ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromosome passenger complex
Cellular Componentcytoplasm
Cellular Componentkinetochore
Cellular Componentspindle microtubule
Cellular Componentspindle midzone
Cellular Componentspindle pole centrosome
Molecular FunctionATP binding
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionprotein serine/threonine/tyrosine kinase activity
Biological Processasymmetric protein localization involved in cell fate determination
Biological Processcentrosome cycle
Biological Processcentrosome separation
Biological Processmitotic centrosome separation
Biological Processmitotic spindle organization
Biological Processpole cell formation
Biological Processregulation of cytokinesis
Biological Processregulation of protein localization
Biological Processsymmetric cell division

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aurora kinase
  • EC number

Gene names

    • Name
      aurA
    • Synonyms
      aur
    • ORF names
      CG3068

Organism names

  • Taxonomic identifier
  • Strains
    • Canton S
    • Oregon R
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q27393

Organism-specific databases

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link291Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-19Basic and acidic residues
Region1-93Disordered
Compositional bias71-93Polar residues
Region106-156Disordered
Compositional bias120-137Polar residues
Compositional bias138-154Basic and acidic residues
Domain164-416Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    421
  • Mass (Da)
    47,204
  • Last updated
    1996-11-01 v1
  • Checksum
    DF35F5C78C10D1DC
MSHPSDHVLRPKENAPHRMPEKSAAVLNMQKNLLLGKKPNSENMAPDSKPLPGSSGALIRSAATTVRPATKPGLGGSNSIASSEGNNFQKPMVPSVKKTTSEFAAPAPVAPIKKPESLSKQKPTAASSESSKELGAASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLDQVMVHPWILAHTQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-19Basic and acidic residues
Compositional bias71-93Polar residues
Compositional bias120-137Polar residues
Compositional bias138-154Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X83465
EMBL· GenBank· DDBJ
CAA58468.1
EMBL· GenBank· DDBJ
mRNA
X83466
EMBL· GenBank· DDBJ
CAA58469.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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