Q24UJ6 · Q24UJ6_DESHY

Function

function

Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

Catalytic activity

  • Preferential cleavage: (Ac)2-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.
    EC:3.4.16.4 (UniProtKB | ENZYME | Rhea)

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for active site, binding site.

137950100150200250300350
TypeIDPosition(s)Description
Active site72Acyl-ester intermediate
Active site75Proton acceptor
Active site127
Binding site234substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionserine-type D-Ala-D-Ala carboxypeptidase activity
Biological Processpeptidoglycan biosynthetic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    serine-type D-Ala-D-Ala carboxypeptidase
  • EC number

Gene names

    • Ordered locus names
      DSY2507

Organism names

Accessions

  • Primary accession
    Q24UJ6

Proteomes

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-26
ChainPRO_500420233227-379serine-type D-Ala-D-Ala carboxypeptidase

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain281-368Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal

Sequence similarities

Belongs to the peptidase S11 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    379
  • Mass (Da)
    41,091
  • Last updated
    2006-04-18 v1
  • Checksum
    A5C3DCD69FA3DC2E
MFKQKWTQAGVCVLISLSLSAAPVYAQTTDTNQGLIPTSSLAITADAAVLMDGATGDILYDKNAHKQRPPASTTKILTAILGLELGKPDELVVVSEKAAAVGESTIHLDPGEKILLYELVTGAMVKSGNDACVAIAEQIAGTEEDFVRLMNQKAFLLGAKNTHFENTNGLPNKNHVSTAYDLALMARYGLQIPAFTSITRLKETEIHFIEPDFFMNLRNTNKLLWNYPYTDGVKTGTTTAAGKCLVAGATKDGRQLIAVVLHAPDRFGDAQKLLEWGFNETETLNCVQAGETIEFPAENSEPIKAFAQNPIQISILKTDKEKLEKKIVWTREPGLPIKAGDSLGAYEVWLNGEKLGSTPLYAESSVKPKGRLSNLLEGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP008230
EMBL· GenBank· DDBJ
BAE84296.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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