Q24MW7 · Q24MW7_DESHY
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids673 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- Na+(in) + diphosphate + H2O = Na+(out) + 2 phosphate + H+Na+ (in)CHEBI:29101
+ CHEBI:33019 + CHEBI:15377 = Na+ (out)CHEBI:29101+ 2 CHEBI:43474 + CHEBI:15378
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 460 | Determinant of potassium dependence | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Desulfitobacteriaceae > Desulfitobacterium
Accessions
- Primary accessionQ24MW7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 12-31 | Helical | |||
Transmembrane | 62-79 | Helical | |||
Transmembrane | 85-103 | Helical | |||
Transmembrane | 124-151 | Helical | |||
Transmembrane | 157-178 | Helical | |||
Transmembrane | 229-248 | Helical | |||
Transmembrane | 254-278 | Helical | |||
Transmembrane | 290-310 | Helical | |||
Transmembrane | 322-344 | Helical | |||
Transmembrane | 386-413 | Helical | |||
Transmembrane | 461-481 | Helical | |||
Transmembrane | 493-517 | Helical | |||
Transmembrane | 565-584 | Helical | |||
Transmembrane | 591-613 | Helical | |||
Transmembrane | 654-672 | Helical | |||
Keywords
- Cellular component
Interaction
Structure
Sequence
- Sequence statusComplete
- Length673
- Mass (Da)68,980
- Last updated2006-04-18 v1
- ChecksumD0F153F5EF49748E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP008230 EMBL· GenBank· DDBJ | BAE86625.1 EMBL· GenBank· DDBJ | Genomic DNA |