Q24MW7 · Q24MW7_DESHY

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site460Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA
    • Ordered locus names
      DSY4836

Organism names

Accessions

  • Primary accession
    Q24MW7

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-31Helical
Transmembrane62-79Helical
Transmembrane85-103Helical
Transmembrane124-151Helical
Transmembrane157-178Helical
Transmembrane229-248Helical
Transmembrane254-278Helical
Transmembrane290-310Helical
Transmembrane322-344Helical
Transmembrane386-413Helical
Transmembrane461-481Helical
Transmembrane493-517Helical
Transmembrane565-584Helical
Transmembrane591-613Helical
Transmembrane654-672Helical

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    673
  • Mass (Da)
    68,980
  • Last updated
    2006-04-18 v1
  • Checksum
    D0F153F5EF49748E
MTMDFASTPIWAVLAGLVGLAFAFYFASSVLKESPGNARMQEISLAIQEGAMAFLNRQYKTLIPFVIIIFLILTFLKGWQTAVSFLVGALLSAVAGYVGMGITTRANARTTEAARTSLNKALGVSFRAGAVMGLSVNGLGLIGVAALFLWFQDAETINSFAFGASAIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDTAGMGADLFESYAATTIAAMLIGAVAFKSLGGGVSGLMLPLMIGIAGILSSIIASFFVRTGENANPQTALNKGLWGTNLLTAIASYAIVQLMITEPVHVSESLTLTANNIFIAIVCGLVVNILIGLLTEYYTSNQKAPAQAIAKASETGAATNIIQGLATGMKSTALPVVVICVATYVSFAAAGIFGIAMAAMAMLSTAGMVVAIDSFGPVADNAGGIAEMADLDPSVRKTTDKLDSVGNTTAAVAKGFAIGSAALTALALFNAYSELAHLDRIDILVPTTIIGLFIGAALPFLFSAFAMEAVGKAAFEMIGEVRRQFREIPGLMEGKAKPDYRACVDISTKAAIRQMIVPGLLAIGSPILVGFLLGKDALGGMLAGGTVSGLLMAIFMANAGGAWDNAKKYVEAGNLGGKGTPTHAAAVIGDTVGDPFKDTAGPSLNALIKVMGTISLIIAPLLI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP008230
EMBL· GenBank· DDBJ
BAE86625.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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