Q22401 · NAS21_CAEEL

  • Protein
    Zinc metalloproteinase-like protein nas-21
  • Gene
    nas-21
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

May lack metalloprotease activity.

Caution

Ser-137 is present instead of the conserved His which is expected to be zinc-binding residue. There is therefore some uncertainty concerning the enzymatic activity of this protein.

Features

Showing features for active site.

138050100150200250300350
TypeIDPosition(s)Description
Active site138

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processmolting cycle, collagen and cuticulin-based cuticle
Biological Processproteolysis

Names & Taxonomy

Protein names

  • Recommended name
    Zinc metalloproteinase-like protein nas-21
  • Alternative names
    • Nematode astacin 21

Gene names

    • Name
      nas-21
    • ORF names
      T11F9.5

Organism names

  • Taxonomic identifier
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q22401
  • Secondary accessions
    • Q7Z0M8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, signal, propeptide, glycosylation, disulfide bond.

Type
IDPosition(s)Description
ChainPRO_0000028925?-380Zinc metalloproteinase-like protein nas-21
Signal1-24
PropeptidePRO_000044266825-?
Glycosylation87N-linked (GlcNAc...) asparagine
Disulfide bond90↔233
Disulfide bond110↔130
Glycosylation253N-linked (GlcNAc...) asparagine
Glycosylation269N-linked (GlcNAc...) asparagine
Glycosylation283N-linked (GlcNAc...) asparagine
Glycosylation304N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain46-234Peptidase M12A

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    380
  • Mass (Da)
    44,626
  • Last updated
    2008-04-08 v3
  • MD5 Checksum
    9685FCC3A7DBC48C9FDEC05CF0F6230C
MNYFITFFFMHIAVLNFYFRFSNGNKIVMRVGGSPETKRLERSKRQALRMDNEPRWPRGTINYFFDEQRFDENSRATVLRAMEKISNHTCIKFSPKDARIKLRIVSDKGCQAAIGRVGGDQQYLSFPTSCYSVGSASELIHVIGFLHSHQRADRDEYLKLNLQPWRLNDWFQTMQYKKYLDQWWIVPYDYGSIMQYHDSDNEYGPKNSKYFRTMGSQIPSYFDYLMINEYYQCSCEGEEQINCKNRGYPNPGNCSECNCPLESSEEWKNITLNLDAGYMSLQNGTKLHQIDFVFRYLSISAPANKTIEVDIREITGVECNYGCYIGGIEVKTHEDRRMTSPRLCCKNDNEIYKSRNNPTIVMAFNSEGLDKYNIFYRFTD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z74042
EMBL· GenBank· DDBJ
CAA98533.2
EMBL· GenBank· DDBJ
Genomic DNA
AJ561211
EMBL· GenBank· DDBJ
CAD99213.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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