Q22323 · STPP_CAEEL

  • Protein
    Steroid-phosphate phosphatase
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Phosphatase that dephosphorylates some steroids such as ecdysone 22-phosphate (E22P), 3-epi-ecdysone 22-phosphate (E22P) and 3-epi-ecdysone 2-phosphate (E2P) in vitro (PubMed:17348005).
Also displays acid phosphatase activity towards 4-nitrophenyl phosphate (pNNP) in vitro (PubMed:17348005).
Has no activity towards 3-epi-ecdysone 3-phosphate (E3P) in vitro (PubMed:17348005).

pH Dependence

Active at pH 4 and 7.4.

Features

Showing features for active site.

128320406080100120140160180200220240260280
TypeIDPosition(s)Description
Active site10
Active site11Tele-phosphohistidine intermediate
Active site194

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionacid phosphatase activity
Molecular Functionphosphatase activity
Molecular Functionphosphoprotein phosphatase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Steroid-phosphate phosphatase
  • EC number
  • Alternative names
    • Protein UBASH3A homolog

Gene names

    • ORF names
      T07F12.1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q22323

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004573561-283Steroid-phosphate phosphatase

Proteomic databases

Expression

Gene expression databases

    • WBGene00020321Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    283
  • Mass (Da)
    32,458
  • Last updated
    2004-03-01 v2
  • Checksum
    9E1E2AEDDCC69712
MPERRVFIIRHGERCDFAFGKSGLWINSFDSRGRYRPLDINLPRTLPKRADGWQGFAADTPLTEIGYLQSKLTGRALRDNGIEINHVFCSPALRCIQTTVGLLKGMGLDKRIQFSVEPGLYEWMVFARYARPCWIPPKDLKKLGYPVQENYVPCWTDKELRMNETLADFYQRSFGSINKILSECTEGNILIVAHGASLETCTRQLVGGDIRSTDDFYYLLQNTPYLSCVEVNSREGLWRLVGSPIPSFSHTYNRTFDPLQLVTKDLASLKREREGKDNMRTTQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284606
EMBL· GenBank· DDBJ
CCD70850.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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