Q214L6 · RIMO_RHOPB

Function

function

Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site16[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site52[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site81[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site148[4Fe-4S] cluster 2 (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site152[4Fe-4S] cluster 2 (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site155[4Fe-4S] cluster 2 (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular Functionprotein methylthiotransferase activity
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribosomal protein uS12 methylthiotransferase RimO
  • EC number
  • Short names
    uS12 MTTase
    ; uS12 methylthiotransferase
  • Alternative names
    • Ribosomal protein uS12 (aspartate-C(3))-methylthiotransferase
    • Ribosome maturation factor RimO

Gene names

    • Name
      rimO
    • Ordered locus names
      RPC_2620

Organism names

Accessions

  • Primary accession
    Q214L6

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003749721-441Ribosomal protein uS12 methylthiotransferase RimO

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-117MTTase N-terminal
Domain134-371Radical SAM core
Domain374-440TRAM

Sequence similarities

Belongs to the methylthiotransferase family. RimO subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    441
  • Mass (Da)
    48,776
  • Last updated
    2006-04-18 v1
  • Checksum
    4A10D6DB6D54CDDA
MNQAAAPKVSFVSLGCPKALVDSERIITRLRAEGYELARKHDGADLVIVNTCGFLDSAKKESLGAIGEAMAANGKVIVTGCMGAEPEQIEAAYPNLLSITGPQQYESVLDAVHRALPPLHNPHLDLVPAQGIKLTPRHYAYLKISEGCNNRCSFCIIPKLRGDLVSRPAGEVLREAEKLVKAGVKELLVVSQDTSAYGVDLKYAESPWQDRNVRARFYDLAKELGELGAWVRLQYVYPYPHVDEVIGLMAQGKVLPYLDIPFQHASPEVLKQMKRPAAQDKTLARIKQWREICPELTLRSTFIVGFPGETDSDFAYLLDWLEQAEIDRVGAFKYEAVRGATSNALPDQVSDEVKTERWNALMARQQKISARRLKRKVGTRQQVIIDEVGPTVSKGRSKADAPQIDGSVYLTSRRPLRVGEIVTAKIERADAYDLHGSVAGF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000301
EMBL· GenBank· DDBJ
ABD88170.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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