Q21041 · VER4_CAEEL

  • Protein
    Tyrosine-protein kinase receptor ver-4
  • Gene
    ver-4
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Receptor tyrosine kinase which may be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail.

Features

Showing features for binding site, active site.

112161002003004005006007008009001,0001,1001,200
TypeIDPosition(s)Description
Binding site876-884ATP (UniProtKB | ChEBI)
Binding site908ATP (UniProtKB | ChEBI)
Active site1042Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functiontransmembrane receptor protein tyrosine kinase activity
Biological Processnematode male tail tip morphogenesis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine-protein kinase receptor ver-4
  • EC number
  • Alternative names
    • Vascular endothelial growth factor receptor related 4

Gene names

    • Name
      ver-4
    • ORF names
      F59F3.5

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q21041

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Single-pass type I membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-789Extracellular
Transmembrane790-810Helical
Topological domain811-1216Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation, disulfide bond.

TypeIDPosition(s)Description
ChainPRO_00004345161-1216Tyrosine-protein kinase receptor ver-4
Glycosylation142N-linked (GlcNAc...) asparagine
Glycosylation195N-linked (GlcNAc...) asparagine
Glycosylation206N-linked (GlcNAc...) asparagine
Glycosylation245N-linked (GlcNAc...) asparagine
Glycosylation283N-linked (GlcNAc...) asparagine
Glycosylation333N-linked (GlcNAc...) asparagine
Glycosylation348N-linked (GlcNAc...) asparagine
Glycosylation384N-linked (GlcNAc...) asparagine
Glycosylation402N-linked (GlcNAc...) asparagine
Glycosylation412N-linked (GlcNAc...) asparagine
Glycosylation496N-linked (GlcNAc...) asparagine
Glycosylation508N-linked (GlcNAc...) asparagine
Glycosylation588N-linked (GlcNAc...) asparagine
Glycosylation599N-linked (GlcNAc...) asparagine
Disulfide bond619↔675
Glycosylation664N-linked (GlcNAc...) asparagine
Glycosylation703N-linked (GlcNAc...) asparagine
Disulfide bond721↔765

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain596-691Ig-like C2-type 1
Domain697-783Ig-like C2-type 2
Domain870-1181Protein kinase

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,216
  • Mass (Da)
    140,906
  • Last updated
    2008-12-16 v2
  • Checksum
    67AFC63D918F177D
MRVSLTEFLVLAQVVTTLQPITIKVDFHEVKHHESIGDYVELVEGKNRDISLTCYGQHKNLKIEPPKREEHAGFPEIGIRTSAEWKKNEYWFLLKNVRQCDTGSYYCVSDEFKESMLQNTVHIFVRKLDIFVPLKTIYHEHNGSEIIIPCKTTKFVDTKNVELYVNQVKLNSALQGYDQRYGFKLTKNMYTMKPNSTVFFECKYTNDSNQDLDYYISNSDPDATLIDQYFFYWEKSNDVPYVGNNYSITCHLVYIGSDSLRPLNHQEIVLECPQNQCDGGYNNQSAHEIEKRSSGLRFGDPSSQDIVEKNTMLRYDRLSVYDRKTSRTVNFQNLTSEDSGIYRCTWRNRSKTNIVLDYDLNFNQKGTQIKIIETSKQRLKMRKNESTLLFVKFAVFPINKKNYTAKWSRLYNSTVEGGQQVETIRNGFFRQITTKTSGRNVFLETLNLKSPKIEMSGIYVLSISNMDIVQQVKWIIEVENDEPNAQLTIRDPLTLNISNQLFLPLNTNLSIFCLAVSSSPTDVIFEYRTDENEWFRGFYKNKLRKIDDTFEKGFIYNFVLAKRTDFKCINVKKKKTSTKFITVTSNANKTFHEIEKSVNATKTEPSDIIFEGDNVRLTCVVPYGAVEFDVFWKFENPKMLKYTTFPAMHPVKDRYKRVILNVRNITIDFTGTYYCIVKNKEFEHRFETSISVEKVSPPFLLNNNSRSIISASNGQMFDINCKVNGVPTPDYTWFKDGYPYTKGKVIGNALHVSKAEKRDNGIFWCSATNRAGTTIDYIEVKVAGASSSSFFWLFITFFAFVVVGIVVSLLWKLFGQKDLKPSELSLNNLKRATDEYQKYTVSEKINNLPVEERIDYLTYNEDYEIDLENLEILETLGSGQFGIVKKGYLNMASSKNFGFESRLSVAIKSSTDSSNMELQKMFFEELKLMCAIPKHPNVLSLVGAVTKNMEIGELFIVTELIDGGNLREFLRERRDVFANELVEKGYIFLTNVRENVPKREVEKEQLLIDEFNSLCTSDLLSIGLQIANGMDWLANIPCVHRDLACRNVLISKTKIIRIADFGLAKKHTDKAYYRVRESLDTPLPVRWMPLESITDLTFTQKSDVWSYGICLYEIFTLGGTPYPDCPNFSLVEYIKTGNINKRPSNCHKDVYKIMKMCWQASPDDRPTFAECIKLFKNHIQYFASKLLQQIEKDLECEKNNQQKFHYWVQKPTQLFF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284606
EMBL· GenBank· DDBJ
CAA91991.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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