Q1YGD3 · Q1YGD3_AURMS

Function

function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N2-acetylornithine and glutamate.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N2-acetyl-L-ornithine (cyclic): step 1/1.
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 1/4.

Features

Showing features for site, binding site, active site.

TypeIDPosition(s)Description
Site123Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Site124Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Binding site160substrate
Binding site186substrate
Site196-197Cleavage; by autolysis
Active site197Nucleophile
Binding site197substrate
Binding site287substrate
Binding site410substrate
Binding site415substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionacetyl-CoA:L-glutamate N-acetyltransferase activity
Molecular Functionglutamate N-acetyltransferase activity
Molecular Functionmethione N-acyltransferase activity
Biological Processarginine biosynthetic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

Including 2 domains:

  • Recommended name
    Glutamate N-acetyltransferase
  • EC number
  • Alternative names
    • Ornithine acetyltransferase
      (OATase
      )
    • Ornithine transacetylase
  • Recommended name
    Amino-acid acetyltransferase
  • EC number
  • Alternative names
    • N-acetylglutamate synthase
      (AGSase
      )

Gene names

    • Name
      argJ
    • ORF names
      SI859A1_02893

Organism names

Accessions

  • Primary accession
    Q1YGD3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50232615571-196Arginine biosynthesis bifunctional protein ArgJ alpha chain
ChainPRO_5023261556197-415Arginine biosynthesis bifunctional protein ArgJ beta chain

Keywords

Interaction

Subunit

Heterotetramer of two alpha and two beta chains.

Family & Domains

Sequence similarities

Belongs to the ArgJ family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    415
  • Mass (Da)
    42,620
  • Last updated
    2006-05-02 v1
  • Checksum
    FA81774F425571F8
MAQSTPVSPLAPTELAALPPIDGMRIATAAAGIKYKGRTDVLMMVFDAPAAVAGVFTTSRCPSAPVDHCRASLGGGTARAVVVNSGNANAFTGRRGRQATEATAEAAADAVGATPREVFLASTGVIGEPLDAHKFTGLLAGLAETAGADGWRSAADAIMTTDTYPKLATRQVAVDGVTVTINGIAKGAGMIAPDMATMLSFVATDAAIAAPALQAMLSQAVAPSFNSVTVDSDTSTSDTLLLFATGAAAARGGATIETADDPRLDGFRVALSELLLDLARQVARDGEGARKEIQVTVEGATSDAAAKRIALSIANSPLVKTAVAGEDANWGRVVMAVGKAGEEADRDRLAIHFGDIRVAVDGERDPDYSEDAAAAVMRRAEIPIRVDLGLGQGRWTVYTCDLTKEYVAINGDYRS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAPJ01000005
EMBL· GenBank· DDBJ
EAS49292.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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