Q1YG11 · Q1YG11_AURMS
- Protein5-hydroxyisourate hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids122 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Catalytic activity
- 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 12 | substrate | ||||
Sequence: H | ||||||
Binding site | 51 | substrate | ||||
Sequence: R | ||||||
Binding site | 119 | substrate | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | hydroxyisourate hydrolase activity | |
Biological Process | purine nucleobase metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name5-hydroxyisourate hydrolase
- EC number
- Short namesHIU hydrolase ; HIUHase
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Aurantimonadaceae > Aurantimonas
Accessions
- Primary accessionQ1YG11
Proteomes
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 9-121 | Transthyretin/hydroxyisourate hydrolase | ||||
Sequence: LTTHVLDTSLGRPGSGIAVALTRLGPDGSRTLVAEAVTNADGRCDAPLMAGDAFAIGEYELVFAAGAYFDAMGIDLQEPKFLGDVVLRFGIAERSHYHVPLLLSPFGYSTYRG |
Sequence similarities
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length122
- Mass (Da)12,907
- Last updated2006-05-02 v1
- Checksum4DB6B36B545D840E
Keywords
- Technical term