Q1YDT1 · Q1YDT1_AURMS
- ProteinAconitate hydratase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids919 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
Catalytic activity
- (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.
Organic acid metabolism; propanoate degradation.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2-methylisocitrate dehydratase activity | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | aconitate hydratase activity | |
Molecular Function | metal ion binding | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAconitate hydratase
- EC number
- Short namesAconitase
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Aurantimonadaceae > Aurantimonas
Accessions
- Primary accessionQ1YDT1
Proteomes
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 78-588 | Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha | ||||
Sequence: AGHEIAYRPARVLMQDFTGVPAVVDLAAMRDATRALGADPKKVNPLVPVDLVIDHSVMVDYFGQKDSFTKNVDAEYGRNGERYTFLRWGSEAFENFRVVPPGTGICHQVNLEYLAQTVWTRDENGETVAYPDTLVGTDSHTTMVNGLSVLGWGVGGIEAEAAMLGQPISMLIPEVIGFRMEGKLPEGTTATDLVLTVTEMLRRRGVVGKFVEFFGPGLSNLTLEDQATIANMAPEYGATCGFFPIDKDTIAYLEATGRDKDRIALVEAYAKAQGMYREDGTPDPVFTDTLELDLSTVVPSLAGPKRPQDRVALTEAATKFVDALAEIKGGRKKSETPQSTADSRYMDEGAVPPNTTPGDVRHAVEGADHGLADGDVVIAAITSCTNTSNPNVLVAAGLVARKAHEKGLKVKPWVKTSLAPGSQVVTEYLDKADLQKDLDALGFNLVGYGCTTCIGNSGPLPEPISEAITQNDLVACSVLSGNRNFEGRVNPDVRANYLASPPLVVAYALAG | ||||||
Region | 406-428 | Disordered | ||||
Sequence: GGRKKSETPQSTADSRYMDEGAV | ||||||
Domain | 722-845 | Aconitase A/isopropylmalate dehydratase small subunit swivel | ||||
Sequence: SHQVRPVDFNSYGARRGNHEVMMRGTFANIRIKNEMVPGVEGGVTCHQPSGAQMPIYDAAMKYKDEGVPLVIFAGKEYGTGSSRDWAAKGTVLLGVRAVIAESFERIHRSNLVGMGVVPFVFAE |
Sequence similarities
Belongs to the aconitase/IPM isomerase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length919
- Mass (Da)100,350
- Last updated2006-05-02 v1
- ChecksumE091D283A11C1028
Keywords
- Technical term