Q1W761 · Q1W761_STREE
- ProteinrRNA adenine N-6-methyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids191 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- adenosine2085 in 23S rRNA + 2 S-adenosyl-L-methionine = 2 H+ + N6-dimethyladenosine2085 in 23S rRNA + 2 S-adenosyl-L-homocysteine
RHEA-COMP:10238 CHEBI:74411 Position: 2085+ 2 CHEBI:59789 = 2 CHEBI:15378 + RHEA-COMP:10237 CHEBI:74493 Position: 2085+ 2 CHEBI:57856
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 1 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: I | ||||||
Binding site | 17 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 38 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 63 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 80 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: N |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | RNA binding | |
Molecular Function | rRNA (adenine-N6,N6-)-dimethyltransferase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namerRNA adenine N-6-methyltransferase
- EC number
- Alternative names
Organism names
- Organism
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionQ1W761
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-159 | Ribosomal RNA adenine methylase transferase N-terminal | ||||
Sequence: IIKQLNFKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIPYHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHT |
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length191
- Mass (Da)22,520
- Last updated2006-05-02 v1
- Checksum062741230A2445D0
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: I | ||||||
Non-terminal residue | 191 | |||||
Sequence: F |