RNA binding protein HuD mediates the crosstalk between beta cells and islet endothelial cells by the regulation of Endostatin and Serpin E1 expression.
we demonstrated HuD downregulation and HuB upregulation in DRG sensory neurons induced by diabetes which might be correlated with altered post-transcriptional control of RNAs involved in the regulation of thermal hypoalgesia condition caused by the advanced diabetic neuropathy.
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