Q1RLX4 · TPC11_DANRE
- ProteinTrafficking protein particle complex subunit 11
- Genetrappc11
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1132 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | Golgi apparatus | |
Biological Process | Golgi organization | |
Biological Process | lipid homeostasis | |
Biological Process | liver development | |
Biological Process | protein N-linked glycosylation | |
Biological Process | protein secretion | |
Biological Process | regulation of response to endoplasmic reticulum stress | |
Biological Process | retina development in camera-type eye | |
Biological Process | vesicle-mediated transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameTrafficking protein particle complex subunit 11
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ1RLX4
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Pronounced hepatomegaly accompanied by lipid accumulation in the liver.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000348075 | 1-1132 | Trafficking protein particle complex subunit 11 | |||
Sequence: MSPARWDLPPELCCRPMAFVALTGLDVVYNAIHRAIWDAFCANRRADRVPISFKVLPGDHEYPKCRTKRTSYEWYIPKGILKTGWMNKHLNLVPALVVLFYELDWDDPQWKEKQSECATKVEIVRTSLQGRNTKVAVVLIQKKTPLPPGEDLVASERASALCGACDLSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYNEIRRVKSHKEFLNKTTHQLLFVRHQFKMGFFSELKQDTQNALKYYRTAYSLVHELRAHETNVLEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHTAWMSKQFQSFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQQAGQLCSHEPGVGYPAPDPLETTSGALDFYGQRPWRQGHQSIDPPDSEKEKQGILALQVKERDVLHSELIIALLSNAVAQFKKYKCPRMKSHLMVQMGEEYYHAKDYTKALKLLDYVMCDYRTERWWSLLTSIVCTALKCSYLMGQVKDYITYSMELVGRASILSEEQKSRIEKNLIKVLMNEVPEPEPDCDPVSVKAAQSLWSDRVSLAGNNEFTIDVQDYVPFVQCKAKFLSPSFHIDEPVQLHVYVRADCPHPVRFSKLCVSLSNQEYNQYCLLEDAYKGKDILEPSSQENMCLVPGKTRKYCFNFVAKTEDVGKKIEITSVGLMLGRETGRYVYLNWRGGWGDAASSHESLQASRSFKRRTRLPEQHVDWDAVSVQSSTMIISRVPKISVQLTHEPPALTNEMFCMTVTIKSEEDTVGKDIKLTAGLKPGQDANLTQSTQITLNGSEVCDDSHPALLPDIPLGDLQPGQKIVKPLYIRCVSTGSRIFLFHVAYSVSATVEGKDITCKCHKDETVTVETVVPFEVAMKFVSSKFEHLERVYVDIPFLLMMDILSASPWPIELVESEVQLASSMTAIDQPQSQVEGVTLQTSECASECFLLKCPPVQNGTSTVASGHYIISWKRKSTFTETSVVRTVITLPHVMVENIPLYVHAEVPSFGRVRESLPVRYHLENRTGLVQDVEISVEPSDAFMFSGLKQVRMRILPGAEQEMLYNFYPLMAGYQVLPQLNINLLRFPNISSQLLRRFLPSRIFVKPQGRNGDASIEAA |
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Component of the multisubunit TRAPP (transport protein particle) complex.
Protein-protein interaction databases
Structure
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q1RLX4-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length1,132
- Mass (Da)128,647
- Last updated2006-05-16 v1
- ChecksumEBA227724FE58452
Q1RLX4-2
- Name2
- Differences from canonical
- 339-938: Missing
Features
Showing features for sequence conflict, alternative sequence.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 5 | in Ref. 1; AAT68061 and 2; AAH56800 | ||||
Sequence: R → Q | ||||||
Alternative sequence | VSP_035103 | 339-938 | in isoform 2 | |||
Sequence: Missing | ||||||
Sequence conflict | 1118 | in Ref. 2; AAH56800 | ||||
Sequence: V → I |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY648743 EMBL· GenBank· DDBJ | AAT68061.1 EMBL· GenBank· DDBJ | mRNA | ||
BC056800 EMBL· GenBank· DDBJ | AAH56800.1 EMBL· GenBank· DDBJ | mRNA | ||
BC115242 EMBL· GenBank· DDBJ | AAI15243.1 EMBL· GenBank· DDBJ | mRNA |