Q1R519 · DLGD_ECOUT

Function

function

Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.

Catalytic activity

Features

Showing features for active site, binding site.

133250100150200250300
TypeIDPosition(s)Description
Active site44Proton donor
Binding site168-174NAD+ (UniProtKB | ChEBI)
Binding site224-225NAD+ (UniProtKB | ChEBI)
Binding site304-306NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-dehydro-L-gulonate 2-dehydrogenase activity
Molecular FunctionNAD+ binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    2,3-diketo-L-gulonate reductase
  • EC number
  • Short names
    2,3-DKG reductase
  • Alternative names
    • 3-dehydro-L-gulonate 2-dehydrogenase

Gene names

    • Name
      dlgD
    • Ordered locus names
      UTI89_C4117

Organism names

Accessions

  • Primary accession
    Q1R519

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000624431-3322,3-diketo-L-gulonate reductase

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    332
  • Mass (Da)
    36,601
  • Last updated
    2006-05-16 v1
  • Checksum
    F329FEFE03F9B01C
MKVTFEQLKAAFNRVLISRGVDNETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTEDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000243
EMBL· GenBank· DDBJ
ABE09545.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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