Q1R519 · DLGD_ECOUT
- Protein2,3-diketo-L-gulonate reductase
- GenedlgD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids332 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
Catalytic activity
- 3-dehydro-L-gulonate + NAD+ = 2,3-dioxo-L-gulonate + H+ + NADH
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | 3-dehydro-L-gulonate 2-dehydrogenase activity | |
Molecular Function | NAD+ binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2,3-diketo-L-gulonate reductase
- EC number
- Short names2,3-DKG reductase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionQ1R519
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000062443 | 1-332 | 2,3-diketo-L-gulonate reductase | |||
Sequence: MKVTFEQLKAAFNRVLISRGVDNETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTEDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL |
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length332
- Mass (Da)36,601
- Last updated2006-05-16 v1
- ChecksumF329FEFE03F9B01C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000243 EMBL· GenBank· DDBJ | ABE09545.1 EMBL· GenBank· DDBJ | Genomic DNA |