Q1R3R3 · G6PI_ECOUT
- ProteinGlucose-6-phosphate isomerase
- Genepgi
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids549 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
Catalytic activity
- alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 355 | Proton donor | |||
Active site | 386 | ||||
Active site | 514 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | carbohydrate derivative binding | |
Molecular Function | glucose-6-phosphate isomerase activity | |
Molecular Function | monosaccharide binding | |
Biological Process | gluconeogenesis | |
Biological Process | glucose 6-phosphate metabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlucose-6-phosphate isomerase
- EC number
- Short namesGPI
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionQ1R3R3
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000252619 | 1-549 | Glucose-6-phosphate isomerase | ||
Modified residue | 80 | N6-acetyllysine | |||
Modified residue | 228 | N6-acetyllysine | |||
Modified residue | 234 | N6-acetyllysine | |||
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Length549
- Mass (Da)61,544
- Last updated2006-10-17 v2
- ChecksumD1ACAC157F068F02
Sequence caution
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000243 EMBL· GenBank· DDBJ | ABE10001.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation |