Q1PYH6 · Q1PYH6_KUEST
- Protein3-oxoacyl-[acyl-carrier-protein] synthase 2
- GenefabF
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids414 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.
Catalytic activity
- (9Z)-hexadecenoyl-[ACP] + H+ + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]
- a fatty acyl-[ACP] + H+ + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]
Pathway
Lipid metabolism; fatty acid biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 165 | For beta-ketoacyl synthase activity | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 3-oxoacyl-[acyl-carrier-protein] synthase activity | |
Biological Process | fatty acid biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-oxoacyl-[acyl-carrier-protein] synthase 2
- EC number
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Planctomycetota > Candidatus Brocadiia > Candidatus Brocadiales > Candidatus Brocadiaceae > Candidatus Kuenenia
Accessions
- Primary accessionQ1PYH6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-413 | Ketosynthase family 3 (KS3) | ||||
Sequence: RKRVVITGTGAITSLGREKKELWSALCNGESGIKPITSFDTTAFEVKFGGEVSDFNPAEWLDTKEARRLDRFSQFAIAATDIAVTDAGLNFDAIDTARVGVFIGSGMGGLLEFEAQHKNLLNKGPSRVSPFMVPKLMANAASAHAAIRYGLRGPNFAVVAACTTGVISIGEAVRVIQRGDADIMITGSSEAVITPLAVAGFGAMKALSTHNSEPQKASRPFDKNRDGFVISEGAGIVVIEELEAAKKRGATIYAEILGYGMTADAYHIAAPNSNGEGAIRCMTHALNDAGCGVETIDYINAHATSTPLGDQIEVGAIKKVFGDHASKIPVSSTKSMLGHQLGASGSVEIIICAFALNEGVIPPTINYETPDPQCSGLDFVPNEAREKKIHKTLSNSFGFGGHNATIILGK |
Sequence similarities
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length414
- Mass (Da)43,578
- Last updated2006-05-16 v1
- ChecksumF9197DAA193C4013
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CT573072 EMBL· GenBank· DDBJ | CAJ72131.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP049055 EMBL· GenBank· DDBJ | QII10511.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LT934425 EMBL· GenBank· DDBJ | SOH03681.1 EMBL· GenBank· DDBJ | Genomic DNA |