Q1K6N8 · MOT1_NEUCR
- ProteinMolybdate transporter 1
- Genemot-1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids541 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Exports stored molybdate from the vacuole into the cytosol, making it available for molybdate cofactor (Moco) biosynthesis (PubMed:36240974).
Plays a role in molybdate homeostasis as high cytosolic levels of molybdate are toxic to cells (PubMed:36240974).
Not required for molybdate import into cells (PubMed:36240974).
Plays a role in molybdate homeostasis as high cytosolic levels of molybdate are toxic to cells (PubMed:36240974).
Not required for molybdate import into cells (PubMed:36240974).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | vacuolar membrane | |
Molecular Function | molybdate ion transmembrane transporter activity | |
Biological Process | molybdate ion export from vacuole |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameMolybdate transporter 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Sordariomycetidae > Sordariales > Sordariaceae > Neurospora
Accessions
- Primary accessionQ1K6N8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Vacuole membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 24-44 | Helical | ||||
Sequence: LLLSEISGSLGDLGTLLPLLL | ||||||
Transmembrane | 58-78 | Helical | ||||
Sequence: LLFSGLFNILTGLVFGVPLPV | ||||||
Transmembrane | 98-118 | Helical | ||||
Sequence: TVAAGAWVGFAVLLLGGTGGL | ||||||
Transmembrane | 137-157 | Helical | ||||
Sequence: AGMSLVVAAGGGMVRPLGWLW | ||||||
Transmembrane | 168-188 | Helical | ||||
Sequence: GLGEWLDSRALAVLAFGGLVV | ||||||
Transmembrane | 214-234 | Helical | ||||
Sequence: MPVQVPYALVLFLVGIMFAVV | ||||||
Transmembrane | 287-307 | Helical | ||||
Sequence: MAIAQLPLTTLNSIIAASALA | ||||||
Transmembrane | 413-433 | Helical | ||||
Sequence: IILLGLTKFLLGLFFPGPGLL | ||||||
Transmembrane | 435-455 | Helical | ||||
Sequence: LLGKFPKAFLGVMVLGAGVEL |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Resistance to molybdate.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000457662 | 1-541 | Molybdate transporter 1 | |||
Sequence: MFFTKPRLHRIITHNLHHLLSPHLLLSEISGSLGDLGTLLPLLLALSLQGSIDLPSTLLFSGLFNILTGLVFGVPLPVQPMKAIAAASLQENADLETTVAAGAWVGFAVLLLGGTGGLKRVMRWVPGAVVRGVQVGAGMSLVVAAGGGMVRPLGWLWTPEENENGHGGLGEWLDSRALAVLAFGGLVVGLGQQQQQQQQSGEKPQERRKKRSKMPVQVPYALVLFLVGIMFAVVRVSLSKDSPQSPPPPPHDQPTNSAPPWTWIWNPLNHIHPKVFRSLLNPQALSMAIAQLPLTTLNSIIAASALASDLFPPDSYPQLYADDESSDSPLSPSPSASSSSLSSAPPQTPSAETPKPLSSPTSAEEGPVPLTPLSLSISAMNLLSAPFGCMPLCHGSGGLAAQHRFGARSGTSIILLGLTKFLLGLFFPGPGLLGLLGKFPKAFLGVMVLGAGVELARVGVRNVEGEEQDRMVMLMTAGTILAFKNDGVGFLAGMGCYGGFRVAAWLGGGTEKGRGGEQGLLGEEEEEEEQGRVDEESPLLR |
Proteomic databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 193-213 | Disordered | ||||
Sequence: QQQQQQQSGEKPQERRKKRSK | ||||||
Region | 317-366 | Disordered | ||||
Sequence: PQLYADDESSDSPLSPSPSASSSSLSSAPPQTPSAETPKPLSSPTSAEEG | ||||||
Compositional bias | 321-360 | Polar residues | ||||
Sequence: ADDESSDSPLSPSPSASSSSLSSAPPQTPSAETPKPLSSP | ||||||
Region | 510-541 | Disordered | ||||
Sequence: TEKGRGGEQGLLGEEEEEEEQGRVDEESPLLR |
Sequence similarities
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length541
- Mass (Da)56,957
- Last updated2011-06-28 v1
- Checksum8F3FD8EAC27CF93C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 321-360 | Polar residues | ||||
Sequence: ADDESSDSPLSPSPSASSSSLSSAPPQTPSAETPKPLSSP |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM002240 EMBL· GenBank· DDBJ | EAA31472.1 EMBL· GenBank· DDBJ | Genomic DNA |