Q1IGA3 · DCUP_PSEE4

Function

function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.

Features

Showing features for binding site, site.

135450100150200250300350
Type
IDPosition(s)Description
Binding site27-31substrate
Binding site77substrate
Site77Transition state stabilizer
Binding site154substrate
Binding site209substrate
Binding site327substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionuroporphyrinogen decarboxylase activity
Biological Processprotoporphyrinogen IX biosynthetic process from glutamate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uroporphyrinogen decarboxylase
  • EC number
  • Short names
    UPD
    ; URO-D

Gene names

    • Name
      hemE
    • Ordered locus names
      PSEEN0339

Organism names

Accessions

  • Primary accession
    Q1IGA3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000239471-354Uroporphyrinogen decarboxylase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    354
  • Mass (Da)
    38,934
  • Last updated
    2006-06-13 v1
  • MD5 Checksum
    07DC74F0E06E94D724BF9ADF8EED1130
MTALKNDRFLRALLKQPVDVTPVWMMRQAGRYLPEYRASRAKAGDFMSLCMNPQFACEVTLQPLDRYPLDAAILFSDILTIPDAMGQGLYFETGEGPRFKKVISTLADIEALPIPDPQKDLGYVMDAVSTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFRKTKAMAYDNPQALHLLLDKLAQSVTSYLNGQILAGAQAVQIFDTWGGNLSAAAYQEFSLAYMRKIVSGLIREHEGRKVPVILFTKNGGLWLESIAEAGADALGLDWTCEIGDARRRVGDKVALQGNMDPTVLYAKPEAIRKEVARILASYGKGSGHVFNLGHGITPEVDPEHAGVFINAVHELSAQYHQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CT573326
EMBL· GenBank· DDBJ
CAK13299.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help