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Q1GLQ4 · Q1GLQ4_RUEST

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site11ADP (UniProtKB | ChEBI)
Binding site11ATP (UniProtKB | ChEBI)
Binding site11sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site12ATP (UniProtKB | ChEBI)
Binding site13ATP (UniProtKB | ChEBI)
Binding site15ADP (UniProtKB | ChEBI)
Binding site81glycerol (UniProtKB | ChEBI)
Binding site81sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site82glycerol (UniProtKB | ChEBI)
Binding site82sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site133glycerol (UniProtKB | ChEBI)
Binding site133sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site242glycerol (UniProtKB | ChEBI)
Binding site242sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site243glycerol (UniProtKB | ChEBI)
Binding site264ADP (UniProtKB | ChEBI)
Binding site264ATP (UniProtKB | ChEBI)
Binding site307ADP (UniProtKB | ChEBI)
Binding site307ATP (UniProtKB | ChEBI)
Binding site311ATP (UniProtKB | ChEBI)
Binding site409ADP (UniProtKB | ChEBI)
Binding site409ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • Ordered locus names
      TM1040_3440

Encoded on

  • Plasmid megaplasmid TM1040

Organism names

Accessions

  • Primary accession
    Q1GLQ4

Proteomes

    • Identifier
    • Component
      Plasmid megaplasmid TM1040

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-249Carbohydrate kinase FGGY N-terminal
Domain260-448Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    494
  • Mass (Da)
    53,318
  • Last updated
    2006-06-27 v1
  • MD5 Checksum
    529ADF604DF283A1C6C3ECC3BF167ED9
MTYILAIDQGTTSTRAILFDGDMQVAAVAQEEFTQHYPNAGWVEHDPEDLWSTTLATCRKVMADKGISASDIAGIGITNQRETTVVWDKATGRAIHNAIVWQDRRTAEICEGLRDEGHEDMVRETTGLLLDPYFSGTKVKWILDTVEGARARAEAGDLLFGTIDSFLIWRLTNGQSHVTDATNAARTLMYDIKSGSWSTEICAMLEVPQAMLPDVLDSAADFGTTSPDHFGGAIPILGVAGDQQAATVGQTCFKPGMMKSTYGTGCFALLNTGDTPVLSKNRMLTTIAYQLDGKPTYALEGSIFIAGAAVQWLRDGLGIIGKASESGVLADKADPTQDVILVPAFTGLGAPYWEPDCRGGMFGLTRNSGPAEFARAALQSVAYQTRDLWEAMRADWEGEANVTLRVDGGMSASDWAMQSLSDTLGAAVDRPVMQETTALGAAWLAGMKAGVYPDQEGFAATWALDREFKPKLDAARREEAYARWKRAVQAVIGV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000376
EMBL· GenBank· DDBJ
ABF62412.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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