Q1GA99 · RECU_LACDA
- ProteinHolliday junction resolvase RecU
- GenerecU
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids210 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.
Catalytic activity
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 87 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 89 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 102 | Mg2+ (UniProtKB | ChEBI) | |||
Site | 104 | Transition state stabilizer | |||
Binding site | 121 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | endonuclease activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleic acid binding | |
Biological Process | chromosome segregation | |
Biological Process | DNA recombination | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHolliday junction resolvase RecU
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus
Accessions
- Primary accessionQ1GA99
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000016728 | 1-210 | Holliday junction resolvase RecU | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length210
- Mass (Da)24,040
- Last updated2006-06-27 v1
- ChecksumD43797AE72FCB77E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR954253 EMBL· GenBank· DDBJ | CAI97815.1 EMBL· GenBank· DDBJ | Genomic DNA |