Q1CT37 · SPEE_HELPH
- ProteinPolyamine aminopropyltransferase
- GenespeE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids262 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
Catalytic activity
- putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H+ + S-methyl-5'-thioadenosine + spermidine
Pathway
Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | spermidine synthase activity | |
Biological Process | spermidine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyamine aminopropyltransferase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Helicobacteraceae > Helicobacter
Accessions
- Primary accessionQ1CT37
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000012002 | 1-262 | Polyamine aminopropyltransferase | |||
Sequence: MWITQEITPYLRKEYTIEAKLLDVRSEHNILEIFKSKDFGEIAMLNCQLLFKNFLHIESELLAHMGGCTKKELKEVLIVDGFDLELAHQLFKYDTHIDFVQADEKILDSFISFFPHFHEVKNNKNFTHAKQLLDLDIKKYDLILCLQEPDIHKMDGLKRMLKEDGVFISVAKHPLLEHVSMQNALKNMGGVFSVAMPFVAPLRILSNKGYIYASFKTHPLKDLMTPKIEALTSMRYYNEDIHRAAFALPKNLQEVFKDNIKS |
Interaction
Subunit
Homodimer or homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-249 | PABS | ||||
Sequence: MWITQEITPYLRKEYTIEAKLLDVRSEHNILEIFKSKDFGEIAMLNCQLLFKNFLHIESELLAHMGGCTKKELKEVLIVDGFDLELAHQLFKYDTHIDFVQADEKILDSFISFFPHFHEVKNNKNFTHAKQLLDLDIKKYDLILCLQEPDIHKMDGLKRMLKEDGVFISVAKHPLLEHVSMQNALKNMGGVFSVAMPFVAPLRILSNKGYIYASFKTHPLKDLMTPKIEALTSMRYYNEDIHRAAFALP |
Sequence similarities
Belongs to the spermidine/spermine synthase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length262
- Mass (Da)30,474
- Last updated2006-07-11 v1
- ChecksumAC2C2A2D407A112B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000241 EMBL· GenBank· DDBJ | ABF84885.1 EMBL· GenBank· DDBJ | Genomic DNA |