Q1AHB5 · Q1AHB5_PSEAI

  • Protein
    Enoyl-[acyl-carrier-protein] reductase [NADH]
  • Gene
    fabV
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).

Catalytic activity

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site48-53NAD+ (UniProtKB | ChEBI)
Binding site74-75NAD+ (UniProtKB | ChEBI)
Site75Plays an important role in discriminating NADH against NADPH
Binding site111-112NAD+ (UniProtKB | ChEBI)
Binding site139-140NAD+ (UniProtKB | ChEBI)
Binding site225substrate
Active site235Proton donor
Binding site244NAD+ (UniProtKB | ChEBI)
Binding site273-275NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
Molecular FunctionNAD binding
Molecular Functiontrans-2-enoyl-CoA reductase (NADH) activity
Biological Processfatty acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Enoyl-[acyl-carrier-protein] reductase [NADH]
  • EC number
  • Short names
    ENR

Gene names

    • Name
      fabV

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • PA68
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    Q1AHB5

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-80Trans-2-enoyl-CoA reductase-like NAD(P)H binding
Domain82-317Trans-2-enoyl-CoA reductase catalytic
Domain323-386Enoyl reductase FAD binding

Sequence similarities

Belongs to the TER reductase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    398
  • Mass (Da)
    43,514
  • Last updated
    2006-07-11 v1
  • Checksum
    8A63D511AC824ACC
MIIKPRVRGFICVTTHPAGCEANVKQQIDYVEAKGPVVNGPKKVLVIGSSTGYGLAARITAAFGSGADTLGVFFERPGSESKPGTAGWYNSATFEKFAHEKGLYARSINGDAFSDEVKRLTIETIKRDLGKVDLVVYSLAAPRRTHPKSGEVFSSTLKPIGKSVSFRGLDTDKEVIKDVVLEAASDQEVADTVAVMGGEDWQMWIDALLEADVLADGAKTTAFTYLGEKITHDIYWNGSIGAAKKDLDQKVLGIRDKLAPLGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKEQGTHEGCIEQVDGLYRESLYGAEPRLDDEGRLRADYKELQPEVQSRVEELWDKVTNENLYELTDFAGYKSEFLNLFGFEVAGVDYEQDVNPGVRIANLIQA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ097892
EMBL· GenBank· DDBJ
AAZ52557.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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