Q186Z6 · ASSY_CLOD6
- ProteinArgininosuccinate synthase
- GeneargG
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids399 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-citrulline + L-aspartate + ATP = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H+
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 8-16 | ATP (UniProtKB | ChEBI) | |||
Binding site | 87 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 92 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 117 | ATP (UniProtKB | ChEBI) | |||
Binding site | 119 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 123 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 123 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 124 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 127 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 176 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 185 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 261 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 273 | L-citrulline (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | argininosuccinate synthase activity | |
Molecular Function | ATP binding | |
Biological Process | argininosuccinate metabolic process | |
Biological Process | L-arginine biosynthetic process | |
Biological Process | urea cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameArgininosuccinate synthase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillati > Bacillota > Clostridia > Peptostreptococcales > Peptostreptococcaceae > Clostridioides
Accessions
- Primary accessionQ186Z6
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000263913 | 1-399 | Argininosuccinate synthase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length399
- Mass (Da)44,624
- Last updated2006-07-25 v1
- MD5 ChecksumD296F5BF61DAC08CB2517D123BC29490
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AM180355 EMBL· GenBank· DDBJ | CAJ68655.1 EMBL· GenBank· DDBJ | Genomic DNA |