Q18331 · GCY11_CAEEL
- ProteinReceptor-type guanylate cyclase gcy-11
- Genegcy-11
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids1168 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).
Catalytic activity
- GTP = 3',5'-cyclic GMP + diphosphate
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 964 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 964 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 965 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 1008 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 1008 | Mg2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | adenylate cyclase activity | |
Molecular Function | ATP binding | |
Molecular Function | GTP binding | |
Molecular Function | guanylate cyclase activity | |
Molecular Function | metal ion binding | |
Molecular Function | peptide receptor activity | |
Molecular Function | protein kinase activity | |
Biological Process | cGMP biosynthetic process | |
Biological Process | intracellular signal transduction | |
Biological Process | protein phosphorylation | |
Biological Process | receptor guanylyl cyclase signaling pathway |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameReceptor-type guanylate cyclase gcy-11
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionQ18331
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Topological domain | 19-517 | Extracellular | |||
Transmembrane | 518-538 | Helical | |||
Topological domain | 539-1168 | Cytoplasmic | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-18 | ||||
Chain | PRO_0000433280 | 19-1168 | Receptor-type guanylate cyclase gcy-11 | ||
Glycosylation | 62 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 82 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 474 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 481 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 512 | N-linked (GlcNAc...) asparagine | |||
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, coiled coil.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 562-888 | Protein kinase | |||
Coiled coil | 896-934 | ||||
Domain | 959-1089 | Guanylate cyclase | |||
Domain
The protein kinase domain is predicted to be catalytically inactive.
Sequence similarities
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length1,168
- Mass (Da)131,443
- Last updated2021-04-07 v5
- Checksum8F11C246C0B8A4A1
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX284606 EMBL· GenBank· DDBJ | CCD63635.3 EMBL· GenBank· DDBJ | Genomic DNA |