Q18331 · GCY11_CAEEL

  • Protein
    Receptor-type guanylate cyclase gcy-11
  • Gene
    gcy-11
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).

Catalytic activity

Features

Showing features for binding site.

111681002003004005006007008009001,0001,100
TypeIDPosition(s)Description
Binding site964Mg2+ 1 (UniProtKB | ChEBI)
Binding site964Mg2+ 2 (UniProtKB | ChEBI)
Binding site965Mg2+ 2 (UniProtKB | ChEBI)
Binding site1008Mg2+ 1 (UniProtKB | ChEBI)
Binding site1008Mg2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenylate cyclase activity
Molecular FunctionATP binding
Molecular FunctionGTP binding
Molecular Functionguanylate cyclase activity
Molecular Functionmetal ion binding
Molecular Functionpeptide receptor activity
Molecular Functionprotein kinase activity
Biological ProcesscGMP biosynthetic process
Biological Processintracellular signal transduction
Biological Processprotein phosphorylation
Biological Processreceptor guanylyl cyclase signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Receptor-type guanylate cyclase gcy-11
  • EC number

Gene names

    • Name
      gcy-11
    • ORF names
      C30G4.3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q18331

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Single-pass type I membrane protein

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain19-517Extracellular
Transmembrane518-538Helical
Topological domain539-1168Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

Type
IDPosition(s)Description
Signal1-18
ChainPRO_000043328019-1168Receptor-type guanylate cyclase gcy-11
Glycosylation62N-linked (GlcNAc...) asparagine
Glycosylation82N-linked (GlcNAc...) asparagine
Glycosylation474N-linked (GlcNAc...) asparagine
Glycosylation481N-linked (GlcNAc...) asparagine
Glycosylation512N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in pharyngeal muscle.

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, coiled coil.

Type
IDPosition(s)Description
Domain562-888Protein kinase
Coiled coil896-934
Domain959-1089Guanylate cyclase

Domain

The protein kinase domain is predicted to be catalytically inactive.

Sequence similarities

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    1,168
  • Mass (Da)
    131,443
  • Last updated
    2021-04-07 v5
  • Checksum
    8F11C246C0B8A4A1
MPCREIFLLWILVPIASSSDHITFFGRYACNVDFKTDYCTPDTYVGRAFYYGLEDGGGITTNGTFVNSDITVEFFDPTVQGNFSIGRQDGNYMSSMLDIMLADTKKNDGLLGVVGVENDCKEIAALAQAYDASSLLVNCEDQVGESQMPSSTALQMSSTQGGKYRAFAKLAKSVGWNNLAVINFVEDGPADISYHDQLLDALSAESISLDFVKKGGFSSTITSAMFTGLESVIDVILETYMKTRIYVIVLDLPVSGTFFMNAMSTMGLLETGKYFVVMMSSIESDAANYFGFNVNRGNMIFKTIDYGISDADIRQYYRSFMYFTDVPHYTKDFSDEWTSFQKRVDGDASKTFCPPMCNTKAKGIANNDPWSDDAYWYSESPSIVDAYDLGRLLSETVKVHGASLLRDPESLVQTMSGRGVTSLLGYVTKFNTNGVSQREYILWAPQQASSSNGPIPLPEWATLAARMLPDGKGNYSIIWKNLTQLGIFNGELPQSKPECGFNNELCPAGIRNLSELEIIVIAVCVVAILILVGVIAYIARWIAYERRLESSYFLVHRKHVQLVDMTKFGSSRGGSMIQSAMSMRSQYEDSGPVGGATMNFYTNGIRKAAIRRNQMQRSDKGPAANRDEWLEIVDWHLAKYENTLVTVRKINKTQLKLTREMKQEIDLLMNETHENLNRFFGLINESDLIFTIHSYGPRKSLMDLLRNDDLRLDRMFKVSFVEDVVKGLQFLHEGSKIGYHGNLKSSNCIVDAYWRIKLSNYGMEQIRVEEPESKPDDLLWFAPEIIRRYAVKHDLSKLELAKADIYSLAIVLYEIYGRQGPFGDDLLDSDEIIEQLKFPDGGALTRPDIHLITKAPYPLASVVEKCWVEDPASRPSIKKVRELLKPLSKGLKGNIADNIMNLLDRYRNNLEDVIKERTEQLEDERKRNESLLLQLLPKSVANSLKNGQPVDAEFYDSVSIYFSDIVGFTALSSKSTPLQVVNMLNNLYTNFDTIIDKFDCYKVETIGDAYMFVSGLPEVNSYLHAGEVASASLELLDSIKTFTVSHCPDEKLRLRIGNHTGPVVTGVVGIRMPRYCLFGDTVIIANMMESSGEPMRIQISSDAYELILKCGGYVTEQREKIVLKNKLEVMTYWMNDYSKDARLARLVAHQEKFPHLEHLIHKFNKGVR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284606
EMBL· GenBank· DDBJ
CCD63635.3
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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