Q17QH2 · Q17QH2_BOVIN

  • Protein
    Dual specificity mitogen-activated protein kinase kinase 2
  • Gene
    MAP2K2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site101ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcell-cell junction
Cellular Componentcytoplasmic side of plasma membrane
Cellular Componentearly endosome
Cellular Componentendoplasmic reticulum
Cellular Componentfocal adhesion
Cellular ComponentGolgi apparatus
Cellular Componentlate endosome
Cellular Componentmicrotubule
Cellular Componentmitochondrion
Cellular Componentperinuclear region of cytoplasm
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase activity
Molecular FunctionMAP-kinase scaffold activity
Molecular FunctionPDZ domain binding
Molecular Functionprotein serine/threonine kinase activator activity
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionscaffold protein binding
Biological ProcessERK1 and ERK2 cascade
Biological Processpositive regulation of DNA-templated transcription
Biological Processpositive regulation of gene expression
Biological Processregulation of early endosome to late endosome transport
Biological Processregulation of Golgi inheritance
Biological Processregulation of stress-activated MAPK cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity mitogen-activated protein kinase kinase 2
  • EC number
  • Alternative names
    • ERK activator kinase 2
    • MAPK/ERK kinase 2

Gene names

    • Name
      MAP2K2

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    Q17QH2
  • Secondary accessions
    • F1MYR6

Proteomes

Organism-specific databases

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain72-369Protein kinase
Region286-310Disordered

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    400
  • Mass (Da)
    44,502
  • Last updated
    2006-07-25 v1
  • Checksum
    FF7CDABD0A943BD4
MLARRKPVLPALTINPAIAEGPSPTSEGASEAHLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELSIGRYPIPPPDAKELEAIFGRPMVDGAEGEPPSISPRPRPPGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTQDFQEFVNKCLIKNPAERADLKMLMNHTFIKRSEVEEVDFAGWLCKTLRLNQPSTPTRTAV

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0AAA9U2K8A0AAA9U2K8_BOVINMAP2K2383
A0A3S5ZPX3A0A3S5ZPX3_BOVINMAP2K2370

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC118362
EMBL· GenBank· DDBJ
AAI18363.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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