Q153D7 · Q153D7_XENLA

Function

Catalytic activity

Features

Showing features for binding site.

1789100200300400500600700
TypeIDPosition(s)Description
Binding site330ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentbasal plasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functionepidermal growth factor binding
Molecular Functionepidermal growth factor receptor activity
Biological Processnegative regulation of apoptotic process
Biological Processneurogenesis
Biological Processpositive regulation of epithelial cell proliferation
Biological Processpositive regulation of kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    receptor protein-tyrosine kinase
  • EC number

Gene names

    • Name
      egfr

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus

Accessions

  • Primary accession
    Q153D7

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane231-253Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain297-554Protein kinase

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    789
  • Mass (Da)
    87,982
  • Last updated
    2006-07-25 v1
  • Checksum
    7121C5133FED0159
TDLNVFENLEVIRGRTKQRGTYALAIVQRSITALGLQSLKEVSDGDVIIKTNKNLCYVNTINFTNMFRTPKQIKIINDNKNPEQCESEGKVCDTLCSEEGCWGPGPSQCVSCLKYIRGKECVENCNFLSREPRGYTVDGRCFSCNVECLQLNDTQTCSGPGADECFKCAHYSDGPFCVKTCPAGIHGENNSLIWKYPDENGACQLCHPECKLGCAGHGIDGCPPPWSYHSVAAGVVGGILGAVVIGLVAFFFIRRSRINRKRTLRRILQERELVEPVTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYQGLWIPEGEGIKIPVAIKELREATSPKANKEILDEAYVMASVENPYVCRLLGICLTSTVQLITQLMPFGCLLDYVRENKDNIGSRHLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKGPQHVKITDFGLAKLLGADEKAYHAEGGKVPIKWMALESILHRTYTHQSDVWSYGVTVWELMTFGLKPYDGIPASEISNILEKGERLPQPPICTIDVYMIMVKCWMIDAESRPKFRELSAEFTKMARDPTRYLVIQGDDRMHLPSPVESKIHPALVEAGLGDIVDAEEYLLPHQGFFTSPSNSRTPLLSTMSSTSNNSPVICITRNGGLPAREDSFVQRYSTDPTVILEDSIDDEFLPAPEYVNQMVPKPVVETQTNPVYQNLSPSGNTVSPEENLYQNSHSNGLNNPEYLNAGQTFVPKTDFDYSSIWDQKANIQINLDNPDYQQDFFPKEPKTNGHFKIPAAQNPEYLGLAPVSDY

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue789

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ646918
EMBL· GenBank· DDBJ
ABG35749.1
EMBL· GenBank· DDBJ
mRNA

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