Q13607 · OR2F1_HUMAN

  • Protein
    Olfactory receptor 2F1
  • Gene
    OR2F1
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Odorant receptor.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionG protein-coupled receptor activity
Molecular Functionolfactory receptor activity
Biological Processdetection of chemical stimulus involved in sensory perception of smell
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Olfactory receptor 2F1
  • Alternative names
    • Olfactory receptor 2F3
    • Olfactory receptor 2F4
    • Olfactory receptor 2F5
    • Olfactory receptor-like protein OLF3

Gene names

    • Name
      OR2F1
    • Synonyms
      OLF3, OR2F3, OR2F3P, OR2F4, OR2F5

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q13607
  • Secondary accessions
    • A4D2G1
    • Q6IFP7
    • Q96R49
    • Q9UDX1

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-24Extracellular
Transmembrane25-48Helical; Name=1
Topological domain49-57Cytoplasmic
Transmembrane58-79Helical; Name=2
Topological domain80-100Extracellular
Transmembrane101-120Helical; Name=3
Topological domain121-139Cytoplasmic
Transmembrane140-160Helical; Name=4
Topological domain161-200Extracellular
Transmembrane201-222Helical; Name=5
Topological domain223-236Cytoplasmic
Transmembrane237-261Helical; Name=6
Topological domain262-272Extracellular
Transmembrane273-292Helical; Name=7
Topological domain293-317Cytoplasmic

Keywords

Disease & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variantVAR_053136122in dbSNP:rs2072164
Natural variantVAR_053137137in dbSNP:rs2072165

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 748 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Miscellaneous

Genetic variation databases

PTM/Processing

Features

Showing features for chain, glycosylation, disulfide bond.

TypeIDPosition(s)Description
ChainPRO_00001504691-317Olfactory receptor 2F1
Glycosylation5N-linked (GlcNAc...) asparagine
Disulfide bond97↔189

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Organism-specific databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Keywords

Phylogenomic databases

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Complete
  • Length
    317
  • Mass (Da)
    35,350
  • Last updated
    2000-12-01 v2
  • Checksum
    A72ADE1AEB6680CE
MGTDNQTWVSEFILLGLSSDWDTRVSLFVLFLVMYVVTVLGNCLIVLLIRLDSRLHTPMYFFLTNLSLVDVSYATSVVPQLLAHFLAEHKAIPFQSCAAQLFFSLALGGIEFVLLAVMAYDRYVAVCDALRYSAIMHGGLCARLAITSWVSGFISSPVQTAITFQLPMCRNKFIDHISCELLAVVRLACVDTSSNEVTIMVSSIVLLMTPFCLVLLSYIQIISTILKIQSREGRKKAFHTCASHLTVVALCYGVAIFTYIQPHSSPSVLQEKLFSVFYAILTPMLNPMIYSLRNKEVKGAWQKLLWKFSGLTSKLAT

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict211in Ref. 1; AAB01215

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U56421
EMBL· GenBank· DDBJ
AAB01215.1
EMBL· GenBank· DDBJ
Genomic DNA
AC004853
EMBL· GenBank· DDBJ
AAC64376.1
EMBL· GenBank· DDBJ
Genomic DNA
CH236959
EMBL· GenBank· DDBJ
EAL23795.1
EMBL· GenBank· DDBJ
Genomic DNA
CH878732
EMBL· GenBank· DDBJ
EAW55625.1
EMBL· GenBank· DDBJ
Genomic DNA
BC104975
EMBL· GenBank· DDBJ
AAI04976.1
EMBL· GenBank· DDBJ
mRNA
AF399594
EMBL· GenBank· DDBJ
AAK95079.1
EMBL· GenBank· DDBJ
Genomic DNA
BK004215
EMBL· GenBank· DDBJ
DAA04613.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp