Q12Z64 · AMPPA_METBU
- ProteinAMP phosphorylase
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids506 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.
Catalytic activity
- AMP + phosphate = alpha-D-ribose 1,5-bisphosphate + adenine
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 168 | AMP (UniProtKB | ChEBI) | |||
Binding site | 194-199 | AMP (UniProtKB | ChEBI) | |||
Binding site | 203 | AMP (UniProtKB | ChEBI) | |||
Active site | 256 | Proton donor | |||
Binding site | 264 | AMP (UniProtKB | ChEBI) | |||
Binding site | 288 | AMP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 1,4-alpha-oligoglucan phosphorylase activity | |
Molecular Function | AMP binding | |
Molecular Function | pentosyltransferase activity | |
Biological Process | AMP catabolic process | |
Biological Process | pyrimidine deoxyribonucleoside metabolic process | |
Biological Process | pyrimidine nucleobase metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAMP phosphorylase
- EC number
- Short namesAMPpase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanosarcinales > Methanosarcinaceae > Methanococcoides
Accessions
- Primary accessionQ12Z64
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000314720 | 1-506 | AMP phosphorylase | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length506
- Mass (Da)55,123
- Last updated2006-08-22 v1
- ChecksumA44D08052CF1DFDA
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000300 EMBL· GenBank· DDBJ | ABE51262.1 EMBL· GenBank· DDBJ | Genomic DNA |