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Q12XM2 · Q12XM2_METBU

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site71Proton acceptor
Binding site71-72NAD+ (UniProtKB | ChEBI)
Binding site76NAD+ (UniProtKB | ChEBI)
Binding site139-140NAD+ (UniProtKB | ChEBI)
Binding site150NAD+ (UniProtKB | ChEBI)
Binding site167NAD+ (UniProtKB | ChEBI)
Binding site169NAD+ (UniProtKB | ChEBI)
Binding site180-185NAD+ (UniProtKB | ChEBI)
Binding site204NAD+ (UniProtKB | ChEBI)
Binding site239NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      nadK
    • Ordered locus names
      Mbur_0853

Organism names

Accessions

  • Primary accession
    Q12XM2

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    278
  • Mass (Da)
    29,820
  • Last updated
    2006-08-22 v1
  • MD5 Checksum
    8C460CFFD12A45A40E8AE7C3D49CE6A6
MAIKKIGIVSRCDHTDALEMVSSIVDNFGSKVKVALSPNTALPLKLEGVEVIPVELMREHGVELLISVGGDGTVLRNIARMEDPLPILGINMGTVGFLVEVNPSEAISTIEKVLEGFKYSERSRLAIDLNGESIPAATNEVVLTTARPAKILTFRITIDDQKAEEMRADGVVIATPTGSTAYAMSAGGPLIDPAVNATLIVPLAPFKLSARPWVVPASSIIKVEMIVPEKEAALVVDGQYTHTIQKSDVVTLTMSGMPARFVEISASGFYERVQNKLR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000300
EMBL· GenBank· DDBJ
ABE51804.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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