Q12013 · AKR2_YEAST

Function

function

May be involved in constitutive endocytosis of a-factor receptor STE3.

Miscellaneous

Present with 815 molecules/cell in log phase SD medium.

Caution

It is uncertain whether Met-1 or Met-4 is the initiator.

Features

Showing features for active site.

1749100200300400500600700
TypeIDPosition(s)Description
Active site476S-palmitoyl cysteine intermediate

GO annotations

AspectTerm
Cellular Componentfungal-type vacuole
Cellular Componentfungal-type vacuole membrane
Cellular ComponentGolgi apparatus
Cellular ComponentGolgi membrane
Molecular Functionpalmitoyltransferase activity
Molecular Functionprotein-cysteine S-palmitoyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable palmitoyltransferase AKR2
  • EC number
  • Alternative names
    • Ankyrin repeat-containing protein AKR2

Gene names

    • Name
      AKR2
    • ORF names
      OR26.25
    • Ordered locus names
      YOR034C

Organism names

Accessions

  • Primary accession
    Q12013
  • Secondary accessions
    • D6W2A0

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-306Cytoplasmic
Transmembrane307-327Helical
Transmembrane328-348Helical
Topological domain349-360Cytoplasmic
Transmembrane361-381Helical
Topological domain382-392Extracellular
Transmembrane393-413Helical
Topological domain414-489Cytoplasmic
Transmembrane490-510Helical
Topological domain511-546Extracellular
Transmembrane547-567Helical
Topological domain568-749Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00002129361-749Probable palmitoyltransferase AKR2
Glycosylation534N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for repeat, domain.

TypeIDPosition(s)Description
Repeat49-79ANK 1
Repeat83-112ANK 2
Repeat117-146ANK 3
Repeat150-183ANK 4
Repeat189-218ANK 5
Repeat222-251ANK 6
Domain446-496DHHC

Domain

The DHHC domain is required for palmitoyltransferase activity.

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    749
  • Mass (Da)
    85,236
  • Last updated
    1996-11-01 v1
  • Checksum
    887F5A02B9EE030A
MTSMSIIDDENVKKTSNGAAVVTDVAQHAVSDSDNNKAQLLGDGSNTEYVVDIFIEAAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILSGANFYERNNQKQDCFDLAEGMGTKSLFEQALQHHGYDRLGNQKDKLFKKSSHAQFTIFLSPFLLMVYIYLISLVLSPVLAIMLSLLVTVVMVNTLKKFVLPCLPRKNTYKVSLTRTPFFSGLFLSTFCFLIYIWTKKLYPYSVSDYTMKNVQFLVTSFLTVVLFLRLVRSDPGCLKTDDSLTSIQETIKQLIDLGKFDRENFCVETLERKPLRSKYSFFSGALVARYDHYCPWIYNDVGLKNHKLFVFFAVTVQYHMFLFMWLCLAYFKKTNYIYEQVEEYARCALLKNETLCKGSNYDPSTFFLFIWISVNFIWLGAMLIVQFFQILKGITTPELFILIKEEHKAKFINLIPFENSIYTSESKGVEDSDMIPEGPSATTITHTISIDGLEPRNRRRAILSACFSMMGINQWLVTIKEIVGITHILHGQVPQQHHSSLLRSFLVTNHWKTNLTDFWLNSDVTAPLWQRFFYSSDTSKAMLGGTEVDYYELYEYPAREGEVLRPN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X87331
EMBL· GenBank· DDBJ
CAA60751.1
EMBL· GenBank· DDBJ
Genomic DNA
Z74942
EMBL· GenBank· DDBJ
CAA99224.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006948
EMBL· GenBank· DDBJ
DAA10816.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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