Q11129 · MEL_SACMI

Function

Catalytic activity

  • Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.
    EC:3.2.1.22 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site, active site.

147150100150200250300350400450
TypeIDPosition(s)Description
Binding site72substrate
Binding site73substrate
Binding site147substrate
Active site149Nucleophile
Binding site205substrate
Active site209Proton donor
Binding site251substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentextracellular region
Molecular Functionalpha-galactosidase activity
Biological Processglycoside catabolic process
Biological Processmelibiose catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Alpha-galactosidase
  • EC number
  • Alternative names
    • Alpha-D-galactoside galactohydrolase
    • MELj
    • Melibiase

Gene names

    • Name
      MEL

Organism names

  • Taxonomic identifier
  • Strain
    • NBRC 1816
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces

Accessions

  • Primary accession
    Q11129

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
Signal1-18
ChainPRO_000000100719-471Alpha-galactosidase
Disulfide bond42↔74
Glycosylation82N-linked (GlcNAc...) asparagine
Disulfide bond121↔151
Glycosylation175N-linked (GlcNAc...) asparagine
Disulfide bond221↔237
Disulfide bond223↔230
Glycosylation270N-linked (GlcNAc...) asparagine
Glycosylation361N-linked (GlcNAc...) asparagine
Glycosylation370N-linked (GlcNAc...) asparagine
Glycosylation417N-linked (GlcNAc...) asparagine
Glycosylation422N-linked (GlcNAc...) asparagine
Glycosylation435N-linked (GlcNAc...) asparagine
Glycosylation454N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Interaction

Subunit

Homotetramer.

Structure

Family & Domains

Sequence similarities

Belongs to the glycosyl hydrolase 27 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    471
  • Mass (Da)
    52,378
  • Last updated
    1996-11-01 v1
  • Checksum
    9FFF2FA03C03872A
MSYIYLFITAAAVTGALGSSPSYNGLGLTPQMGWDNWNTFACDVSEQLLLNTADRISEIGLKDLGYKYVILDDCWSSGRNSNGTLVADKNKFPNGMDHVARHLHNNNFLFGMYSSAGEYTCAGYPGSLGHEQEDAEFFARNGVDYLKYDNCYNKGKFGTPETSYKRYKAMSDALNKTGRPIFYSLCNWGQDLTFYWGSDIANSWRMSGDIYPEFDRPDSRCPCDGDQYDCSYAGFHCSIMNILNKAAPMGQNAGIGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGADVNHLKESSYSIYSQASVIAINQDPKGVPATRVWRHYVSQTDKYGKGEIQLWSCPLDNGDQVIALLNGSNKKRPMNASLEDIFFDSYLGSEELSSSWDIYDLWANRIDNTIASNILKNNKVTNSSLYNATELSYKEGLSKNDTRLFGVQIGTVSPGGLLNTTVPAHGVALYRLRRSR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X95506
EMBL· GenBank· DDBJ
CAA64760.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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