Q10315 · BUR6_SCHPO

Function

function

Transcription regulator complex subunit that is essential for cell cycle progression.

Caution

SPAC17G8.03c was previously identified as the homolog of budding yeast DBP3 in fission yeast (PubMed:15388803).
However, it was further demonstrated that SPCC16C4.22 is the true ortholog of DBP3 (PubMed:29109278).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromatin
Cellular Componentcytosol
Cellular Componentepsilon DNA polymerase complex
Cellular Componentnegative cofactor 2 complex
Cellular Componentnuclear replication fork
Cellular Componentnucleus
Molecular Functioncore promoter sequence-specific DNA binding
Molecular Functionprotein heterodimerization activity
Molecular FunctionRNA polymerase II general transcription initiation factor activity
Biological ProcessDNA-templated DNA replication
Biological Processtranscription by RNA polymerase II

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription regulator complex subunit bur6

Gene names

    • Name
      bur6
    • ORF names
      SPAC17G8.03c

Organism names

Accessions

  • Primary accession
    Q10315
  • Secondary accessions
    • Q9US69

Proteomes

Organism-specific databases

Phenotypes & Variants

Disruption phenotype

Leads to only a few rounds of cell division before arresting with an elongated cell (cdc) phenotype.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 4 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002083481-199Transcription regulator complex subunit bur6

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias106-182Basic and acidic residues
Region106-199Disordered
Compositional bias183-199Polar residues

Sequence similarities

Belongs to the NC2 alpha/DRAP1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    199
  • Mass (Da)
    22,236
  • Last updated
    1996-10-01 v1
  • Checksum
    96233C2DE4AFFBD8
MGDPTNNNDSETKPNPATYWKSRFPVARIKKIMQADQDVGKVAQVTPVIMSKALELFMQSIIQESCKQTRLHQAKRVTVSHLKHAVQSVEQFDFLQDIVEKVPDAPPIKAERKTKRPRARRAANEGEHNESVPAKKVKKNTVKEEEIEKDDESATTETPVKEEPTGEETEADHEEKASVDHGNFSDKTTSEASSASGDE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias106-182Basic and acidic residues
Compositional bias183-199Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU329670
EMBL· GenBank· DDBJ
CAA93686.1
EMBL· GenBank· DDBJ
Genomic DNA
AB028008
EMBL· GenBank· DDBJ
BAA87312.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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