Q0WTY4 · VPS2B_ARATH

Function

function

Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentESCRT III complex
Biological Processprotein transport
Biological Processvacuolar transport

Keywords

Protein family/group databases

    • 3.A.31.1.2the endosomal sorting complexes required for transport iii (escrt-iii) family

Names & Taxonomy

Protein names

  • Recommended name
    Vacuolar protein sorting-associated protein 2 homolog 2
  • Short names
    AtVPS2-2
  • Alternative names
    • Charged multivesicular body protein 2 homolog 2
    • ESCRT-III complex subunit VPS2 homolog 2

Gene names

    • Name
      VPS2.2
    • Synonyms
      CHMP2-2
    • ORF names
      MFC16.25
    • Ordered locus names
      At5g44560

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q0WTY4
  • Secondary accessions
    • B3H7E8
    • Q84TF3
    • Q9FGV7

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003681961-222Vacuolar protein sorting-associated protein 2 homolog 2

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Component of the endosomal sorting required for transport complex III (ESCRT-III), composed at least of VPS2, VPS20, VPS24 and VPS32 (By similarity).
Interacts with CHMP1A, CHMP1B and VPS60-1 (PubMed:22010978).

Binary interactions

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for coiled coil, region, compositional bias.

TypeIDPosition(s)Description
Coiled coil26-83
Coiled coil143-222
Region179-222Disordered
Compositional bias206-222Basic and acidic residues

Sequence similarities

Belongs to the SNF7 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q0WTY4-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    222
  • Mass (Da)
    24,305
  • Last updated
    2009-04-14 v2
  • Checksum
    C86FB65136DCE0AC
MNIFKKKTTPKDALRTSKREMAVATRGIEREITSLQLEEKRLVAEIKKTAKTGNEAATKILARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQAKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAPKGRIATKTAAPPASTAATNKNSESSEVDELEKRLASLRRI

Q0WTY4-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8BHG3A0A1P8BHG3_ARATHVPS22156
A0A1P8BHG8A0A1P8BHG8_ARATHVPS22186

Sequence caution

The sequence BAB11575.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for alternative sequence, sequence conflict, compositional bias.

TypeIDPosition(s)Description
Alternative sequenceVSP_0368031-20in isoform 2
Sequence conflict199in Ref. 5; AAO64783
Sequence conflict201in Ref. 2; BAE99414 and 5; AAO64783
Compositional bias206-222Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB024024
EMBL· GenBank· DDBJ
BAB11575.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AB017065
EMBL· GenBank· DDBJ
BAB11575.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002688
EMBL· GenBank· DDBJ
AED95123.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED95124.1
EMBL· GenBank· DDBJ
Genomic DNA
AK227410
EMBL· GenBank· DDBJ
BAE99414.1
EMBL· GenBank· DDBJ
mRNA
BT005848
EMBL· GenBank· DDBJ
AAO64783.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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