Q0WRC9 · SKI17_ARATH
- ProteinF-box protein SKIP17
- GeneSKIP17
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids479 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Pathway
Protein modification; protein ubiquitination.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Biological Process | protein ubiquitination |
Keywords
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameF-box protein SKIP17
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ0WRC9
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000283487 | 1-479 | F-box protein SKIP17 | |||
Sequence: MDPPTQSHNSVRTVPGSNHSHTDLIISSFLSFPDSSPISISNSFDRVLDRALASASADESVQDRLVDRTLELASLLLDSTRRCFRKRASVHNSNSWSLPPELTIKVFSMLDTKSMMQAAVCCTMFNKCAMDRLCYSHIDLTTSARYADKGVVSTMINRAGKELRSLKLGRVVRTAGSDSAAPLLSGSCLSPLAYNHGFLGSRLRSLRLYNLRPIKYRSLCDALSVCPNITDLRIVGLYNLTEELFNSLTKKCRLIEHLFLETYGYPRTLESKAGSSLVEFVTNCPNLTSLTLIRFGLTDDWARNLAESCRKLKYLNLSRSPTIKGRFLRELGLSCKENLLKTLILRSCPKLQEKEVLEFCNSLLTGNFKSIRQIDVSSNSGLASSDRGKRCNKPNFPLERLKEERSDVTFVADFPSTSSGKRYGVCDEEELRLIEMMEAEDDEVDEEDDSDDDTDDVSDEDESENDDDMGMGFDVDYLL |
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Part of a SCF (ASK-cullin-F-box) protein ligase complex (By similarity).
Interacts with SPK1B/ASK2
Interacts with SPK1B/ASK2
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q0WRC9 | SKP1B Q9FHW7 | 3 | EBI-604757, EBI-604076 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 92-138 | F-box | ||||
Sequence: NSNSWSLPPELTIKVFSMLDTKSMMQAAVCCTMFNKCAMDRLCYSHI | ||||||
Compositional bias | 435-471 | Acidic residues | ||||
Sequence: EMMEAEDDEVDEEDDSDDDTDDVSDEDESENDDDMGM | ||||||
Region | 435-479 | Disordered | ||||
Sequence: EMMEAEDDEVDEEDDSDDDTDDVSDEDESENDDDMGMGFDVDYLL |
Domain
The F-box is necessary for the interaction with ASK proteins.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length479
- Mass (Da)53,680
- Last updated2006-09-05 v1
- ChecksumD20CD4CEB7E6346A
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8B8P5 | A0A1P8B8P5_ARATH | At4g02740 | 516 |
Sequence caution
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 280 | in Ref. 3; BAD42970 | ||||
Sequence: F → L | ||||||
Compositional bias | 435-471 | Acidic residues | ||||
Sequence: EMMEAEDDEVDEEDDSDDDTDDVSDEDESENDDDMGM |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC004044 EMBL· GenBank· DDBJ | AAD15349.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AL161495 EMBL· GenBank· DDBJ | CAB77759.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002687 EMBL· GenBank· DDBJ | AEE82223.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK175207 EMBL· GenBank· DDBJ | BAD42970.1 EMBL· GenBank· DDBJ | mRNA | ||
AK228382 EMBL· GenBank· DDBJ | BAF00320.1 EMBL· GenBank· DDBJ | mRNA |