Q0WML3 · SCOP6_ARATH

Function

function

Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation (PubMed:33514716, PubMed:34535661).
Inhibits root growth (PubMed:34535661).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapoplast
Cellular Componentplasma membrane
Molecular FunctionLRR domain binding
Molecular Functionreceptor serine/threonine kinase binding
Biological Processresponse to herbivore
Biological Processresponse to insect
Biological Processresponse to wounding

Names & Taxonomy

Protein names

  • Recommended name
    Serine rich endogenous peptide 6
  • Short names
    AtSCOOP6
  • Alternative names
    • Phytocytokine SCOOP6
    • Precursor of serine rich endogenous peptide phytocytokine 6

Gene names

    • Name
      PROSCOOP6
    • Synonyms
      SCOOP6
    • ORF names
      K15C23
    • Ordered locus names
      At5g44572

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q0WML3

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
Note: The precursor of SCOOP6, PROSCOOP6, accumulates at the plasma membrane and is proteolytically cleaved to release the SCOOP6 in the apoplasm.

Keywords

PTM/Processing

Features

Showing features for peptide, signal, propeptide.

TypeIDPosition(s)Description
PeptidePRO_0000457225?-93Serine rich endogenous peptide 6
Signal1-27
PropeptidePRO_000045722428-?Removed in mature form

Keywords

Proteomic databases

Expression

Tissue specificity

Mostly expressed in seedlings shoots, and, to a lower extent, in roots.

Induction

Accumulates upon infection by generalist herbivores such as Spodoptera littoralis (PubMed:35401621).
Induced by wounding (PubMed:35401621).

Gene expression databases

Interaction

Subunit

Interacts with MIK2 (via extracellular leucine-rich repeat domain); this interaction triggers the formation of complex between MIK2 and the BAK1/SERK3 and SERK4 coreceptors, and subsequent BAK1 activation by phosphorylation.

Family & Domains

Features

Showing features for motif, compositional bias, region.

TypeIDPosition(s)Description
Motif48-62SCOOP motif 1
Compositional bias52-68Polar residues
Region52-93Disordered
Motif54-56SxS motif essential for MIK2 binding
Motif73-87SCOOP motif 2
Compositional bias73-93Basic and acidic residues
Motif79-81SxS motif essential for MIK2 binding

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    93
  • Mass (Da)
    9,928
  • Last updated
    2006-09-05 v1
  • Checksum
    9FBCD3E04A0C5252
MGTKCYSKLRYVVVLVLLLFVFPCSLSQSAPSSVTGRRLMGIYMPNGGIIAGSSPSGQAPNINNNYHGRRLMISEARPSKSKKGGGREPESPG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias52-68Polar residues
Compositional bias73-93Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB024024
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002688
EMBL· GenBank· DDBJ
AED95129.1
EMBL· GenBank· DDBJ
Genomic DNA
AK229806
EMBL· GenBank· DDBJ
BAF01637.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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