Q0WML3 · SCOP6_ARATH
- ProteinSerine rich endogenous peptide 6
- GenePROSCOOP6
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation (PubMed:33514716, PubMed:34535661).
Inhibits root growth (PubMed:34535661).
Inhibits root growth (PubMed:34535661).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | apoplast | |
Cellular Component | plasma membrane | |
Molecular Function | LRR domain binding | |
Molecular Function | receptor serine/threonine kinase binding | |
Biological Process | response to herbivore | |
Biological Process | response to insect | |
Biological Process | response to wounding |
Names & Taxonomy
Protein names
- Recommended nameSerine rich endogenous peptide 6
- Short namesAtSCOOP6
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ0WML3
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: The precursor of SCOOP6, PROSCOOP6, accumulates at the plasma membrane and is proteolytically cleaved to release the SCOOP6 in the apoplasm.
Keywords
- Cellular component
PTM/Processing
Features
Showing features for peptide, signal, propeptide.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Peptide | PRO_0000457225 | ?-93 | Serine rich endogenous peptide 6 | |||
Sequence: MGTKCYSKLRYVVVLVLLLFVFPCSLSQSAPSSVTGRRLMGIYMPNGGIIAGSSPSGQAPNINNNYHGRRLMISEARPSKSKKGGGREPESPG | ||||||
Signal | 1-27 | |||||
Sequence: MGTKCYSKLRYVVVLVLLLFVFPCSLS | ||||||
Propeptide | PRO_0000457224 | 28-? | Removed in mature form | |||
Sequence: MGTKCYSKLRYVVVLVLLLFVFPCSLS |
Keywords
- PTM
Proteomic databases
Interaction
Subunit
Interacts with MIK2 (via extracellular leucine-rich repeat domain); this interaction triggers the formation of complex between MIK2 and the BAK1/SERK3 and SERK4 coreceptors, and subsequent BAK1 activation by phosphorylation.
Structure
Family & Domains
Features
Showing features for motif, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 48-62 | SCOOP motif 1 | ||||
Sequence: GIIAGSSPSGQAPNI | ||||||
Compositional bias | 52-68 | Polar residues | ||||
Sequence: GSSPSGQAPNINNNYHG | ||||||
Region | 52-93 | Disordered | ||||
Sequence: GSSPSGQAPNINNNYHGRRLMISEARPSKSKKGGGREPESPG | ||||||
Motif | 54-56 | SxS motif essential for MIK2 binding | ||||
Sequence: SPS | ||||||
Motif | 73-87 | SCOOP motif 2 | ||||
Sequence: ISEARPSKSKKGGGR | ||||||
Compositional bias | 73-93 | Basic and acidic residues | ||||
Sequence: ISEARPSKSKKGGGREPESPG | ||||||
Motif | 79-81 | SxS motif essential for MIK2 binding | ||||
Sequence: SKS |
Sequence similarities
Belongs to the serine rich endogenous peptide (SCOOP) phytocytokine family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length93
- Mass (Da)9,928
- Last updated2006-09-05 v1
- Checksum9FBCD3E04A0C5252
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 52-68 | Polar residues | ||||
Sequence: GSSPSGQAPNINNNYHG | ||||||
Compositional bias | 73-93 | Basic and acidic residues | ||||
Sequence: ISEARPSKSKKGGGREPESPG |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB024024 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CP002688 EMBL· GenBank· DDBJ | AED95129.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK229806 EMBL· GenBank· DDBJ | BAF01637.1 EMBL· GenBank· DDBJ | mRNA |