Q0W700 · GUAAA_METAR
- ProteinGMP synthase [glutamine-hydrolyzing] subunit A
- GeneguaAA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids189 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the synthesis of GMP from XMP.
Catalytic activity
- XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H+
Pathway
Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 78 | Nucleophile | |||
Active site | 165 | ||||
Active site | 167 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | GMP synthase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameGMP synthase [glutamine-hydrolyzing] subunit A
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Methanobacteriati > Methanobacteriota > Stenosarchaea group > Methanomicrobia > Methanocellales > Methanocellaceae > Methanocella
Accessions
- Primary accessionQ0W700
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000292198 | 1-189 | GMP synthase [glutamine-hydrolyzing] subunit A | ||
Interaction
Subunit
Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length189
- Mass (Da)20,982
- Last updated2006-09-05 v1
- MD5 ChecksumE322D508299C7B58A511C4A5536C6EBF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AM114193 EMBL· GenBank· DDBJ | CAJ35843.1 EMBL· GenBank· DDBJ | Genomic DNA |