Q0VBB8 · Q0VBB8_MOUSE

  • Protein
    Ileal sodium/bile acid cotransporter
  • Gene
    Slc10a2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

Catalytic activity

  • 2 Na+(out) + tauro-beta-muricholate(out) = 2 Na+(in) + tauro-beta-muricholate(in)
  • 2 Na+(out) + tauroallocholate(out) = 2 Na+(in) + tauroallocholate(in)
  • 2 Na+(out) + taurochenodeoxycholate(out) = 2 Na+(in) + taurochenodeoxycholate(in)
  • 2 Na+(out) + taurocholate(out) = 2 Na+(in) + taurocholate(in)
  • 2 Na+(out) + taurodeoxycholate(out) = 2 Na+(in) + taurodeoxycholate(in)
  • 2 Na+(out) + tauronorcholate(out) = 2 Na+(in) + tauronorcholate(in)
  • 2 Na+(out) + tauroursodeoxycholate(out) = 2 Na+(in) + tauroursodeoxycholate(in)
  • cholate(out) + 2 Na+(out) = cholate(in) + 2 Na+(in)
  • glycocholate(out) + 2 Na+(out) = glycocholate(in) + 2 Na+(in)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionsymporter activity
Biological Processlipid transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Ileal sodium/bile acid cotransporter
  • Alternative names
    • Apical sodium-dependent bile acid transporter
    • Ileal Na(+)/bile acid cotransporter
    • Ileal sodium-dependent bile acid transporter
    • Na(+)-dependent ileal bile acid transporter
    • Solute carrier family 10 member 2

Gene names

    • Name
      Slc10a2

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q0VBB8

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane28-47Helical
Transmembrane68-89Helical
Transmembrane95-118Helical
Transmembrane125-148Helical
Transmembrane160-181Helical
Transmembrane193-214Helical
Transmembrane226-245Helical
Transmembrane290-311Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Expression

Gene expression databases

Interaction

Subunit

Monomer and homodimer.

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region328-348Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    348
  • Mass (Da)
    38,134
  • Last updated
    2006-09-05 v1
  • Checksum
    D00B5E43431875D7
MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC120703
EMBL· GenBank· DDBJ
AAI20704.1
EMBL· GenBank· DDBJ
mRNA
BC125290
EMBL· GenBank· DDBJ
AAI25291.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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