Q0VBB8 · Q0VBB8_MOUSE
- ProteinIleal sodium/bile acid cotransporter
- GeneSlc10a2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids348 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- 2 Na+(out) + tauro-beta-muricholate(out) = 2 Na+(in) + tauro-beta-muricholate(in)
2 Na+ (out)CHEBI:29101+ tauro-β-muricholate (out)CHEBI:133064= 2 Na+ (in)CHEBI:29101+ tauro-β-muricholate (in)CHEBI:133064 - 2 Na+(out) + tauroallocholate(out) = 2 Na+(in) + tauroallocholate(in)
- 2 Na+(out) + taurochenodeoxycholate(out) = 2 Na+(in) + taurochenodeoxycholate(in)
- 2 Na+(out) + taurocholate(out) = 2 Na+(in) + taurocholate(in)
- 2 Na+(out) + taurodeoxycholate(out) = 2 Na+(in) + taurodeoxycholate(in)
- 2 Na+(out) + tauronorcholate(out) = 2 Na+(in) + tauronorcholate(in)
- 2 Na+(out) + tauroursodeoxycholate(out) = 2 Na+(in) + tauroursodeoxycholate(in)
- cholate(out) + 2 Na+(out) = cholate(in) + 2 Na+(in)
- glycocholate(out) + 2 Na+(out) = glycocholate(in) + 2 Na+(in)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | symporter activity | |
Biological Process | lipid transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameIleal sodium/bile acid cotransporter
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ0VBB8
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 28-47 | Helical | ||||
Sequence: AILNTVMSTVLTILLAMVMF | ||||||
Transmembrane | 68-89 | Helical | ||||
Sequence: IFVGFLCQFGIMPLTGFILSVA | ||||||
Transmembrane | 95-118 | Helical | ||||
Sequence: VQAVVVLIMGCCPGGTGSNILAYW | ||||||
Transmembrane | 125-148 | Helical | ||||
Sequence: LSVSMTTCSTLLALGMMPLCLFVY | ||||||
Transmembrane | 160-181 | Helical | ||||
Sequence: IPYDSIGISLVALVIPVSFGMF | ||||||
Transmembrane | 193-214 | Helical | ||||
Sequence: ILKIGSITGVILIVLIAVIGGI | ||||||
Transmembrane | 226-245 | Helical | ||||
Sequence: LWIIGTIFPIAGYSLGFFLA | ||||||
Transmembrane | 290-311 | Helical | ||||
Sequence: PLIYTVFQLVFAAVILGIYVTY |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Interaction
Subunit
Monomer and homodimer.
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 328-348 | Disordered | ||||
Sequence: NEMDSRPSFDETNKGFQPDEK |
Sequence similarities
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length348
- Mass (Da)38,134
- Last updated2006-09-05 v1
- ChecksumD00B5E43431875D7
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC120703 EMBL· GenBank· DDBJ | AAI20704.1 EMBL· GenBank· DDBJ | mRNA | ||
BC125290 EMBL· GenBank· DDBJ | AAI25291.1 EMBL· GenBank· DDBJ | mRNA |