Q0VB73 · Q0VB73_MOUSE
- ProteinGranulocyte colony-stimulating factor
- GeneCsf3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids208 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Publications for Q0VB73
Interactions of erythropoietin, granulocyte colony-stimulating factor, stem cell factor, and interleukin-11 on murine hematopoiesis during simultaneous administration.
- CategoriesFunction, Sequences
- SourceMGI: 1339751
- PubMed
- Europe PMC
- Blood 91:3222-3229 ()
Mapped toEssential roles for granulocyte-macrophage colony-stimulating factor (GM- CSF) and G-CSF in the sustained hematopoietic response of Listeria monocytogenes-infected mice.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1339751
- PubMed
- Europe PMC
- Blood 91:863-869 ()
Mapped toMice lacking both granulocyte colony-stimulating factor (CSF) and granulocyte-macrophage CSF have impaired reproductive capacity, perturbed neonatal granulopoiesis, lung disease, amyloidosis, and reduced long-term survival.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1339751
- PubMed
- Europe PMC
- Blood 90:3037-3049 ()
Mapped toFlt3 ligand synergizes with granulocyte-macrophage colony-stimulating factor or granulocyte colony-stimulating factor to mobilize hematopoietic progenitor cells into the peripheral blood of mice.
- CategoryFunction
- SourceMGI: 1339751
- PubMed
- Europe PMC
- Blood 90:3781-3788 ()
Mapped toSynergistic effect of FLT-3 ligand on the granulocyte colony-stimulating factor-induced mobilization of hematopoietic stem cells and progenitor cells into blood in mice.
- CategoryFunction
- SourceMGI: 1339751
- PubMed
- Europe PMC
- Blood 89:3186-3191 ()
Mapped toSelective inhibition of resistance to hemopoietic allografts but not rejection to a natural killer cell sensitive tumor in transgenic mice for granulocyte colony stimulating factor.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1339751
The kinetics of murine hematopoietic stem cells in vivo in response to prolonged increased mature blood cell production induced by granulocyte colony-stimulating factor.
- CategoryFunction
- SourceMGI: 1339751
- PubMed
- Europe PMC
- Blood 86:2986-2992 ()
Mapped toMice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1339751
- PubMed
- Europe PMC
- Blood 84:1737-1746 ()
Mapped toThe inducible nitric oxide synthase gene, Nos2, maps to mouse chromosome 11.
- CategoriesFunction, Sequences
- SourceMGI: 1339751
Association of p72 tyrosine kinase with Stat factors and its activation by interleukin-3, interleukin-6, and granulocyte colony-stimulating factor.
- CategoriesFunction, Interaction
- SourceMGI: 1339751
- PubMed
- Europe PMC
- Blood 83:3457-3461 ()
Mapped toBinding of 125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic cells.
- CategoriesFunction, Sequences
- SourceMGI: 1339751
Squamous cell carcinoma-derived G-CSF promotes tumor growth and metastasis in mice through neutrophil recruitment and tumor cell proliferation, associated with poor prognosis of the patients.
- AnnotationSquamous cell carcinoma-derived G-CSF promotes tumor growth and metastasis in mice through neutrophil recruitment and tumor cell proliferation associated with poor prognosis of the patients.
- CategoryFunction
- SourceGeneRif: 12985
G-CSF exacerbates liver injury in a mouse model of autoimmune hepatitis.
- AnnotationG-CSF exacerbates liver injury in a mouse model of autoimmune hepatitis.
- CategoryFunction
- SourceGeneRif: 12985
G-CSF: A vehicle for communication between trophoblasts and macrophages which may cause problems in recurrent spontaneous abortion.
- AnnotationG-CSF: A vehicle for communication between trophoblasts and macrophages which may cause problems in recurrent spontaneous abortion.
- CategoriesFunction, Expression
- SourceGeneRif: 12985
Role for Granulocyte Colony-Stimulating Factor in Neutrophilic Extramedullary Myelopoiesis in a Murine Model of Systemic Juvenile Idiopathic Arthritis.
- AnnotationRole for Granulocyte Colony-Stimulating Factor in Neutrophilic Extramedullary Myelopoiesis in a Murine Model of Systemic Juvenile Idiopathic Arthritis.
- CategoryFunction
- SourceGeneRif: 12985
Role of melatonin mediated G-CSF induction in hematopoietic system of gamma-irradiated mice.
- AnnotationRole of melatonin mediated G-CSF induction in hematopoietic system of gamma-irradiated mice.
- CategoryFunction
- SourceGeneRif: 12985
Cytokine exposure mediates transcriptional activation of the orphan nuclear receptor Nur77 in hematopoietic cells.
- AnnotationCytokine exposure mediates transcriptional activation of the orphan nuclear receptor Nur77 in hematopoietic cells.
- CategoriesFunction, PTM / Processing
- SourceGeneRif: 12985
The Effects of Tgfb1 and Csf3 on Chondrogenic Differentiation of iPS Cells in 2D and 3D Culture Environment.
- AnnotationThe Effects of Tgfb1 and Csf3 on Chondrogenic Differentiation of iPS Cells in 2D and 3D Culture Environment.
- CategoriesFunction, Expression
- SourceGeneRif: 12985
G-CSF reduces loss of dopaminergic neurons by inhibiting TNF-alpha and IL- 1beta in mouse model of Parkinson's disease.
- AnnotationG-CSF reduces loss of dopaminergic neurons by inhibiting TNF-alpha and IL-1beta in mouse model of Parkinson's disease.
- CategoryFunction
- SourceGeneRif: 12985
Dietary magnesium restriction affects hematopoiesis and triggers neutrophilia by increasing STAT-3 expression and G-CSF production.
- AnnotationDietary magnesium restriction affects hematopoiesis and triggers neutrophilia by increasing STAT-3 expression and G-CSF production.
- CategoriesFunction, Expression
- SourceGeneRif: 12985
GCSF deficiency attenuates nonalcoholic fatty liver disease through regulating GCSFR-SOCS3-JAK-STAT3 pathway and immune cells infiltration.
- AnnotationGCSF deficiency attenuates nonalcoholic fatty liver disease through regulating GCSFR-SOCS3-JAK-STAT3 pathway and immune cells infiltration.
- CategoriesFunction, Phenotypes & Variants
G-CSF shifts erythropoiesis from bone marrow into spleen in the setting of systemic inflammation.
- AnnotationG-CSF shifts erythropoiesis from bone marrow into spleen in the setting of systemic inflammation.
- CategoryFunction
G-CSF and G-CSFR Modulate CD4 and CD8 T Cell Responses to Promote Colon Tumor Growth and Are Potential Therapeutic Targets.
- AnnotationG-CSF and G-CSFR Modulate CD4 and CD8 T Cell Responses to Promote Colon Tumor Growth and Are Potential Therapeutic Targets.
- CategoryFunction
Involvement of Signaling Cascades in Granulocytopoiesis Regulation under Conditions of Cytostatic Treatment.
- AnnotationInvolvement of Signaling Cascades in Granulocytopoiesis Regulation under Conditions of Cytostatic Treatment.
- CategoryFunction
- SourceGeneRif: 12985