Q0TAL3 · UBID_ECOL5

Function

function

Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
prenyl-FMN (UniProtKB | Rhea| CHEBI:87746 )

Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site176Mn2+ (UniProtKB | ChEBI)
Binding site179-181prenyl-FMN (UniProtKB | ChEBI)
Binding site193-195prenyl-FMN (UniProtKB | ChEBI)
Binding site198-199prenyl-FMN (UniProtKB | ChEBI)
Binding site242Mn2+ (UniProtKB | ChEBI)
Active site291Proton donor

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Molecular Functionmetal ion binding
Biological Processubiquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-octaprenyl-4-hydroxybenzoate carboxy-lyase
  • EC number
  • Alternative names
    • Polyprenyl p-hydroxybenzoate decarboxylase

Gene names

    • Name
      ubiD
    • Ordered locus names
      ECP_4056

Organism names

Accessions

  • Primary accession
    Q0TAL3

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002676651-4983-octaprenyl-4-hydroxybenzoate carboxy-lyase

Interaction

Subunit

Homohexamer.

Structure

Family & Domains

Sequence similarities

Belongs to the UbiD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    498
  • Mass (Da)
    55,832
  • Last updated
    2006-09-05 v1
  • Checksum
    299482D865544121
MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIWLDRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000247
EMBL· GenBank· DDBJ
ABG72016.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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