Q0T5Z6 · YMDB_SHIF8

Function

function

Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site11-12substrate
Binding site25substrate
Binding site33-35substrate
Active site35Proton acceptor
Binding site122-126substrate

GO annotations

AspectTerm
Molecular Functiondeacetylase activity
Molecular Functionpurine nucleoside binding
Molecular Functionribonuclease inhibitor activity
Biological Processpurine nucleoside metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-acetyl-ADP-ribose deacetylase
  • EC number
  • Alternative names
    • Regulator of RNase III activity

Gene names

    • Name
      ymdB
    • Ordered locus names
      SFV_1057

Organism names

Accessions

  • Primary accession
    Q0T5Z6

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004094871-177O-acetyl-ADP-ribose deacetylase

Interaction

Subunit

Homodimer. Interacts with RNase III.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-175Macro

Sequence similarities

Belongs to the YmdB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    177
  • Mass (Da)
    18,910
  • Last updated
    2006-09-05 v1
  • Checksum
    6F4E09A31AF70AAF
MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYSYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQQGDE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000266
EMBL· GenBank· DDBJ
ABF03269.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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