Q0RB94 · PANC4_FRAAA

Function

function

Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.

Miscellaneous

The reaction proceeds by a bi uni uni bi ping pong mechanism.

Catalytic activity

Pathway

Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site51-58ATP (UniProtKB | ChEBI)
Active site58Proton donor
Binding site82(R)-pantoate (UniProtKB | ChEBI)
Binding site82beta-alanine (UniProtKB | ChEBI)
Binding site166-169ATP (UniProtKB | ChEBI)
Binding site172(R)-pantoate (UniProtKB | ChEBI)
Binding site195ATP (UniProtKB | ChEBI)
Binding site203-206ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionpantoate-beta-alanine ligase activity
Biological Processpantothenate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pantothenate synthetase 4
  • EC number
  • Short names
    PS 4
  • Alternative names
    • Pantoate--beta-alanine ligase 4
    • Pantoate-activating enzyme 4

Gene names

    • Name
      panC4
    • Ordered locus names
      FRAAL6670

Organism names

Accessions

  • Primary accession
    Q0RB94

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003054561-302Pantothenate synthetase 4

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the pantothenate synthetase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    302
  • Mass (Da)
    31,350
  • Last updated
    2006-09-05 v1
  • Checksum
    CD83BD88735FEE29
MLVRDRAELRAALVALDRAASSHPPAAAQDAGPARAASRHDRPVRAVVMTMGALHEGHASLLRAARARADQVVATIFVNPLQFGAGEDLDRYPRTLAADLAVCAREGVDVVFAPAVIHDPPPLVRFGAGPLGAVLEGASRPGHFDGMLTLVGTMLHLVQPDLAFFGRKDAQQLVCIRRMVADLAFDVTVIGVETAREPDGLARSSRNVYLTAEQRTEALALSRALAAGAAASADGAPAVLAAARAVLDAADGVDVDYLELAGPEDLGPVRGGPALLLVAARVGTTRLIDNVSLILPTDTQGA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CT573213
EMBL· GenBank· DDBJ
CAJ65293.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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