Q0QC74 · Q0QC74_KLEPN
- ProteinL-threonate dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids300 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD+ or NADP+ as cosubstrate, with a preference for NAD+.
Catalytic activity
- L-threonate + NAD+ = 2-dehydro-L-erythronate + NADH + H+
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2-hydroxymethylglutarate dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | organic acid catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-threonate dehydrogenase
- EC number
Encoded on
- Plasmid pK245
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella
Accessions
- Primary accessionQ0QC74
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 7-166 | 6-phosphogluconate dehydrogenase NADP-binding | |||
Domain | 170-289 | 3-hydroxyisobutyrate dehydrogenase-like NAD-binding | |||
Sequence similarities
Belongs to the HIBADH-related family. L-threonate dehydrogenase subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length300
- Mass (Da)30,493
- Last updated2006-09-05 v1
- Checksum816314606D588022
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DQ449578 EMBL· GenBank· DDBJ | ABG56853.1 EMBL· GenBank· DDBJ | Genomic DNA |