Q0JDK9 · DAD1_ORYSJ

  • Protein
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
  • Gene
    DAD1
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

Pathway

Protein modification; protein glycosylation.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentoligosaccharyltransferase complex
Biological Processapoptotic process
Biological Processprotein N-linked glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
  • Short names
    Oligosaccharyl transferase subunit DAD1
  • Alternative names
    • Defender against apoptotic death 1 protein
    • Defender against cell death 1 (DAD-1)

Gene names

    • Name
      DAD1
    • Synonyms
      DAD-1
    • ORF names
      OsJ_014065, OSJNBa0039C07.3
    • Ordered locus names
      Os04g0397000, LOC_Os04g32550

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q0JDK9
  • Secondary accessions
    • B7E891
    • O50070
    • Q7F9I2
    • Q84N35

Proteomes

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-30Cytoplasmic
Transmembrane31-51Helical
Topological domain52-54Lumenal
Transmembrane55-75Helical
Topological domain76-93Cytoplasmic
Transmembrane94-114Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001240281-114Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

Proteomic databases

Interaction

Subunit

Component of the oligosaccharyltransferase (OST) complex.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the DAD/OST2 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    114
  • Mass (Da)
    12,379
  • Last updated
    2006-10-03 v1
  • Checksum
    0BE69A7E935FA301
MPRATSDAKLLIQSLGKAYAATPTNLKIIDLYVVFAVATALIQVVYMGIVGSFPFNSFLSGVLSCIGTAVLAVCLRIQVNKDNKEFKDLPPERAFADFVLCNLVLHLVIMNFLG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
D89726
EMBL· GenBank· DDBJ
BAA24072.1
EMBL· GenBank· DDBJ
mRNA
D89727
EMBL· GenBank· DDBJ
BAA24104.1
EMBL· GenBank· DDBJ
Genomic DNA
AL731591
EMBL· GenBank· DDBJ
CAE05147.2
EMBL· GenBank· DDBJ
Genomic DNA
AP008210
EMBL· GenBank· DDBJ
BAF14578.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014960
EMBL· GenBank· DDBJ
BAS89011.1
EMBL· GenBank· DDBJ
Genomic DNA
CM000141
EMBL· GenBank· DDBJ
EAZ30582.1
EMBL· GenBank· DDBJ
Genomic DNA
AK063198
EMBL· GenBank· DDBJ
BAG88588.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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